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1.
Eur Rev Med Pharmacol Sci ; 28(3): 924-930, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38375697

RESUMO

OBJECTIVE: Floating elbow, which refers to a humerus fracture in the supracondylar region and a forearm fracture, is a very unusual injury. The purpose of this study is to compare the clinical results of patients with "floating elbows" who underwent surgical therapy and who were given forearm immobilization with a splint as follow-up care. PATIENTS AND METHODS: Fifteen patients who had been diagnosed with floating elbow owing to trauma were scanned retrospectively and followed up for at least a year. Eight individuals who suffered from broken forearms underwent surgical repair. After initial treatment, a lengthy arm splint was used to immobilize seven patients' arms. The modified Flynn criteria were used to analyze the data, and comparisons were made between the groups. RESULTS: The median age and mean follow-up time for patients whose forearms were conservatively followed was 6.1 years and 13.8 months, respectively. The median age of the patients who underwent forearm surgery was 8.5 years, and the average follow-up was 14.2 months. Five of the seven patients whose forearms underwent conservative follow-up had outstanding clinical outcomes, while two had poor and moderate outcomes. Four individuals who got surgical treatment for their forearms had excellent and good clinical outcomes, while the other four had intermediate and poor outcomes. Between the two groups, there was no discernible difference (p = 0.60). CONCLUSIONS: In the pediatric population with floating elbow injuries, using a cast for forearm fractures may not necessarily result in worse outcomes compared to surgical management.


Assuntos
Lesões no Cotovelo , Articulação do Cotovelo , Traumatismos do Antebraço , Fraturas do Úmero , Humanos , Criança , Antebraço/cirurgia , Estudos Retrospectivos , Tratamento Conservador , Traumatismos do Antebraço/cirurgia , Traumatismos do Antebraço/epidemiologia , Fraturas do Úmero/diagnóstico por imagem , Fraturas do Úmero/cirurgia , Resultado do Tratamento , Articulação do Cotovelo/diagnóstico por imagem , Articulação do Cotovelo/cirurgia
2.
Eur Rev Med Pharmacol Sci ; 27(23): 11543-11549, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-38095401

RESUMO

OBJECTIVE: Visfatin is currently a cytokine that is extensively researched in the field of bone diseases. In this prospective study, we aimed to investigate the potential of serum visfatin levels as a biomarker for the diagnosis of osteoid osteoma. PATIENTS AND METHODS: This study included a cohort of 20 patients diagnosed with osteoid osteoma (Group 1) and 30 healthy individuals (Group 2). The age, gender, cyst sizes, and visfatin values of all participants were documented and analyzed. RESULTS: There was a significant difference in visfatin levels between the two groups. The median visfatin level in Group 1 was 6.13 ng/ml (IQR: 4.21-8.08), while in Group 2, it was 15.83 ng/ml (IQR: 11.11-20.6). The difference was statistically significant (p<0.000). The optimal cut-off value for visfatin was found to be 7.74 ng/ml, which had a 93% sensitivity and 78% specificity.  An area under the curve of receiver operating characteristic (ROC) analysis of 0.85 indicates good diagnostic performance. CONCLUSIONS: Our study revealed a significant decrease in visfatin levels among patients diagnosed with osteoid osteomas in comparison to the healthy control group. The ROC analysis revealed that visfatin exhibited a commendable diagnostic capacity, indicating its potential utility as a biomarker for osteoid osteoma.


Assuntos
Neoplasias Ósseas , Osteoma Osteoide , Humanos , Biomarcadores , Neoplasias Ósseas/diagnóstico , Citocinas , Nicotinamida Fosforribosiltransferase , Osteoma Osteoide/diagnóstico , Estudos Prospectivos
3.
Eur Rev Med Pharmacol Sci ; 27(24): 11764-11770, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-38164839

RESUMO

OBJECTIVE: Pediatric supracondylar humerus fracture (SCHF) is one of the most common elbow fractures in children aged 5-7 years. There is a continuous discussion regarding the optimal timing for conducting surgery for fractures of this nature. Therefore, we aimed to determine whether the timing of surgery in pediatric SCHFs has an impact on the frequency of early postoperative complications. PATIENTS AND METHODS: Between January 2018 and March 2020, pediatric SCHF patients who underwent surgery at our hospital were retrospectively reviewed. Patients operated on within 12 hours after the fracture and those operated on later were respectively included in the early and late groups. Early postoperative complications, including neurological deficits, iatrogenic ulnar nerve injury, vascular injury, compartment syndrome, K-wire migration, and unexpected returns to the operating room, were compared between the two groups. We investigated surgical duration, reduction, and perioperative radiographic data. RESULTS: For modified Gartland type II or type III fractures, there was no significant difference in the incidence of early complications between the early and delayed groups. Additionally, there were no noticeable differences between the two groups in terms of perioperative radiographic data, reduction procedure, or surgical duration. CONCLUSIONS: Delayed surgery in type II or type III supracondylar humerus fractures was not associated with an increased incidence of early postoperative complications. The difficulty or effectiveness of reduction is not influenced by the timing of surgery.


Assuntos
Fixação Interna de Fraturas , Fraturas do Úmero , Criança , Humanos , Estudos Retrospectivos , Fixação Interna de Fraturas/métodos , Fraturas do Úmero/diagnóstico por imagem , Fraturas do Úmero/cirurgia , Complicações Pós-Operatórias/epidemiologia , Fios Ortopédicos , Resultado do Tratamento
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