RESUMO
The vascular complications arising after the percutaneous transluminal angioplasty (PTA) of the arteriosclerotic stenosis in the right superficial femoral artery of a 70-year old female patient six days prior to her death were studied by means of light microscopy and with the transmission and scanning electron microscopes. The pictures revealed disruption in the vascular wall of the superficial femoral artery, fresh thrombus in the dissecting aneurysm of arteriosclerotic origin in the distal part of the posterior tibial artery and haemorrhage in the media. A connection is suggested between these findings and the angioplastic intervention. To the best of the authors' knowledge this was the first time that in vivo developed vascular changes after PTA were studied by means of light microscopy and with the transmission and scanning electron microscopes.
Assuntos
Angioplastia com Balão/efeitos adversos , Artéria Femoral/patologia , Idoso , Arteriosclerose/patologia , Arteriosclerose/terapia , Feminino , Artéria Femoral/ultraestrutura , Hemorragia/patologia , Humanos , Músculo Liso Vascular/ultraestruturaRESUMO
Finger pulp biopsies of 31 patients suffering from Raynaud's syndrome (RS) were investigated by light and electron microscopy. The patients suffered from various underlying diseases. Interest was focused on the vascular changes and nerve and connective tissue alterations, especially the elastic fiber changes. In the dermal capillaries, endothelial swelling, narrowing of the lumen, increased numbers of intracytoplasmic filaments and Weibel-Palade bodies, and various types of basement membrane alterations were observed. The basement membrane of the unmyelinated nerves showed similar alterations to the capillary basement membrane. Severe degenerative changes were found in the myelin sheath of the myelinated axons. In the dermal connective tissue, severe elastotic degeneration and alterations of the collagen fibers were observed. The data probably represent the ultrastructural picture of the end stage of this syndrome.
Assuntos
Dedos/patologia , Doença de Raynaud/patologia , Adulto , Idoso , Axônios/ultraestrutura , Membrana Basal/ultraestrutura , Capilares/ultraestrutura , Tecido Conjuntivo/ultraestrutura , Citoesqueleto/ultraestrutura , Endotélio/ultraestrutura , Feminino , Humanos , Masculino , Microscopia Eletrônica , Pessoa de Meia-Idade , Músculo Liso Vascular/ultraestrutura , Doença de Raynaud/etiologiaAssuntos
Síndromes do Arco Aórtico/complicações , Síndrome do Roubo Subclávio/complicações , Angiografia , Síndromes do Arco Aórtico/diagnóstico , Velocidade do Fluxo Sanguíneo/métodos , Efeito Doppler , Eletrocardiografia , Humanos , Masculino , Pessoa de Meia-Idade , Síndrome do Roubo Subclávio/diagnósticoAssuntos
Arteriopatias Oclusivas/complicações , Doenças das Artérias Carótidas/diagnóstico , Reologia , Velocidade do Fluxo Sanguíneo/instrumentação , Doenças das Artérias Carótidas/etiologia , Trombose das Artérias Carótidas/diagnóstico , Trombose das Artérias Carótidas/etiologia , Constrição , Efeito Doppler , Feminino , Humanos , Perna (Membro)/irrigação sanguínea , Masculino , Pessoa de Meia-IdadeRESUMO
Disturbances of impulse formation and conduction may arise in the early stage of scleroderma, as a sign of cardiac involvement, termed "scleroderma heart". The incidence of various intraventricular conduction disturbances and their association with other disorders of cardiac rhythm were analysed in 193 scleroderma-patients by age. The presence of ventricular conduction abnormalities was found to carry an increased hazard of the production of disorders of atrioventricular conduction and of abnormal impulse formation. The patients were also followed up for deviation of the R axis in the frontal plane. Septal hypertrophy was found more frequently in patients with intraventricular conduction disturbances than in those free from disorders of this type.
