RESUMO
The article contains ethiopathogenic, clinical and diagnostic criteria of gastroesophageal reflux disease (GERD) in young people. GERD verification was based upon the results of the examination of 137 men aged 18 to 23 years. These results included clinical findings as well as the data from the following tests: intraesophageal and intragastric pH-metry with evaluation of parietal cell response to atropine, and endoscopic and morphological examination of the upper division of the gastrointestinal tract including detection of Helicobacter pylori (HP) expansion, evaluation of inflammatory and regenerative processes in the mucosa of the lower third of the esophagus and the antral part of the stomach. The results show that the feature of GERD in the given age group is a certain morphological picture in the esophagus characterized by a various degree of squamous epithelium dystrophy with almost no metaplasia, as well as a high degree of HP adhesion in the esophagus with atropine-resistent hyperchlorhydria in the stomach. It shoud be noted that eradicational and antisecretory therapy in young people with GERD leads to the reestablishment of the esophagial mucosa structure.
Assuntos
Refluxo Gastroesofágico/etiologia , Adolescente , Adulto , Fatores Etários , Biópsia , Endoscopia do Sistema Digestório , Suco Gástrico/metabolismo , Mucosa Gástrica/microbiologia , Mucosa Gástrica/patologia , Refluxo Gastroesofágico/metabolismo , Refluxo Gastroesofágico/patologia , Helicobacter/isolamento & purificação , Infecções por Helicobacter/metabolismo , Infecções por Helicobacter/microbiologia , Infecções por Helicobacter/patologia , Humanos , Concentração de Íons de Hidrogênio , Masculino , Prognóstico , Índice de Gravidade de DoençaRESUMO
The experience obtained during the treatment of 86 casualties with chest injuries was generalized. The authors present the scheme of diagnosis and treatment for the given patient category. To diagnose the cardiac injuries the operation (pericardium fenestration) was proposed. Application of the proposed scheme for diagnosing and treating the casualties with chest injuries allowed to reduce the number of early pleural complications from 55.1 to 22.1% and diagnostic mistakes--from 34.2 to 11.2%.
Assuntos
Militares , Traumatismos Torácicos/cirurgia , Procedimentos Cirúrgicos Torácicos/métodos , Ferimentos por Arma de Fogo/cirurgia , Adolescente , Adulto , Humanos , Masculino , Pessoa de Meia-Idade , Federação Russa , Resultado do TratamentoAssuntos
Antiulcerosos/uso terapêutico , Benzimidazóis/uso terapêutico , Úlcera Duodenal/tratamento farmacológico , Úlcera Duodenal/patologia , Inibidores Enzimáticos/uso terapêutico , Células Epiteliais/efeitos dos fármacos , Mucosa Gástrica/efeitos dos fármacos , 2-Piridinilmetilsulfinilbenzimidazóis , Apoptose , Úlcera Duodenal/microbiologia , Células Epiteliais/patologia , Mucosa Gástrica/patologia , Mucosa Gástrica/ultraestrutura , Helicobacter pylori , Humanos , Omeprazol/análogos & derivados , ATPases Translocadoras de Prótons/antagonistas & inibidores , RabeprazolAssuntos
Dermatoses da Perna/cirurgia , Transplante de Pele/fisiologia , Infecções Cutâneas Estafilocócicas/cirurgia , Síndrome de Stevens-Johnson/complicações , Adulto , Sobrevivência de Enxerto/fisiologia , Humanos , Dermatoses da Perna/etiologia , Masculino , Infecções Cutâneas Estafilocócicas/etiologia , Cicatrização/fisiologiaRESUMO
The peculiarities of the diagnosis of sepsis in 24 patients with local purulent processes are presented. The DIC-syndrome, pulmonary syndrome, toxic nephropathy are of most importance in diagnosis of the disease.
