The evaluation of stress patterns in porcelain laminate veneers with different restoration designs and loading angles induced by functional loads: A three-dimensional finite element analysis study.

BACKGROUND: Fractures in porcelain laminate veneers (PLVs) are a significant clinical problem. Preparation designs can affect stress distribution, which leads to fractures in PLVs. Therefore, identification of the most favorable preparation design in terms of stress distribution is required. OBJECTIVE: The purpose of this study is to examine the functional stress patterns of PLVs with featheredge, incisal bevel, and overlapped preparation designs under 0°, 60°, and 120° functional loads using finite element analysis. MATERIALS AND METHODS: Porcelain veneers with three different preparation designs (incisal overlap, incisal bevel, and featheredge) were modeled. A cement layer of 100 µm of luting composite resin was assumed, and a thickness of 0.5 mm of porcelain veneers was used. All models were loaded at 0°, 60°, and 120° to the long axis of the tooth to determine the stresses that may occur during mastication under different load angulations. A total force of 200 N was applied from the incisal edge of the models. RESULTS: Maximum stresses were recorded in the incisal overlapped design (53.3 MPa) under 120° of functional load. Minimum stresses were recorded in the incisal bevel preparation design (22.37 MPa) under 0° of functional load. CONCLUSION: Both the preparation design and load angle affected the stress distribution on the PLVs. The incisal bevel preparation design provided a more appropriate geometry for stress distribution compared with the other techniques. Lateral forces produced more stress on the tooth and laminate material than vertical forces.

Inhibitory effects of Turkish folk remedies on inflammatory cytokines: interleukin-1alpha, interleukin-1beta and tumor necrosis factor alpha.

In this study, in vitro inhibitory effects of 55 extracts or fractions obtained from 10 plant species on interleukin-1 (IL-1alpha, IL-1beta) and tumor necrosis factor (TNF-alpha) biosynthesis were studied. The following plant materials from Turkish folk medicine for the treatment of various diseases which are thought to be inflammatory in nature e.g. rheumatism, fever, infections, edemas or related inflammatory diseases were selected as the subject of this study: Cistus laurifolius leaves, Clematis flammna flowering herbs, Crataegus orientalis roots, Daphne oleoides ssp. oleoides whole plant, Ecbalium elaterium roots, Rosa canina roots, Rubus discolor roots, Rubus hirtus roots, Sambucus ebulus flowers and leaves, Sambucus nigra flowers and leaves. All plants showed inhibitory activity against at least one of these models in various percentages depending upon the concentration, thus supporting the folkloric utilization. Daphne oleoides was found to be the most active plant against the test models.