Superhydrophobic nanohybrid sponges for separation of oil/ water mixtures.

The industrial revolution has led to different types of environmental pollution, including frequent leakage of crude oil to marine waters and the contamination of wastewater with immiscible or emulsified oils and organic liquids from various industrial residues. Hence, developing multifunctional materials for oil/water separation is a field of high significance for the remediation of oil-polluted water. Recently, advanced superwetting materials have been employed for oily wastewater treatment. This review summarizes the recent development in fabricating superhydrophobic/superoleophilic nanohybrid polyurethane, melamine, and cellulose sponges for oil/water separation. The use of organic and/or inorganic nanohybrid materials opens the horizon for designing a diverse and wide range of superhydrophobic sponges due to the synergistic effect between the surface roughness and chemical composition. The discussion is organized based on different classes of low surface energy materials including thermoplastics, thermosets, elastomers, fluorinated polymers, conductive polymers, organosilanes, long alkyl chain compounds, and hydrophobic carbon-based materials. Recent examples for the separation of both immiscible and emulsified oil/water mixtures are presented, with a focus on fabrication strategies, separation efficiency, recyclability, mechanical performance, and durability. Currently, most studies did not focus on the mechanical/chemical stability of the fabricated sponges, and hence, future research directions shall address the fabrication of robust and long-term durable superhydrophobic sponges with proper guidelines. Similarly, more research focus is required to design superhydrophobic sponges for the separation of emulsified oil/water mixtures and heavy crude oil samples. Superhydrophobic sponges can be employed for treatment of oily wastewater, emulsion separation, and cleanup of crude oil spills.

Fouling in ocular devices: implications for drug delivery, bioactive surface immobilization, and biomaterial design.

The last 30 years has seen a proliferation of research on protein-resistant biomaterials targeted at designing bio-inert surfaces, which are prerequisite for optimal performance of implantable devices that contact biological fluids and tissues. These efforts have only been able to yield minimal results, and hence, the ideal anti-fouling biomaterial has remained elusive. Some studies have yielded biomaterials with a reduced fouling index among which high molecular weight polyethylene glycols have remained dominant. Interestingly, the field of implantable ocular devices has not experienced an outflow of research in this area, possibly due to the assumption that biomaterials tested in other body fluids can be translated for application in the ocular space. Unfortunately, progression in the molecular understanding of many ocular conditions has brought to the fore the need for treatment options that necessitates the use of anti-fouling biomaterials. From the earliest implanted horsehair and silk seton for glaucoma drainage to the recent mini telescopes for sight recovery, this review provides a concise incursion into the gradual evolution of biomaterials for the design of implantable ocular devices as well as approaches used to overcome the challenges with fouling. The implication of fouling for drug delivery, the design of immune-responsive biomaterials, as well as advanced surface immobilization approaches to support the overall performance of implantable ocular devices are also reviewed.

Application and Characterization of Gum from Bombax buonopozense Calyxes as an Excipient in Tablet Formulation.

This study was undertaken to explore gum from Bombax buonopozense calyxes as a binding agent in formulation of immediate release dosage forms using wet granulation method. The granules were characterized to assess the flow and compression properties and when compressed, non-compendial and compendial tests were undertaken to assess the tablet properties for tablets prepared with bombax gum in comparison with those prepared with tragacanth and acacia gums. Granules prepared with bombax exhibited good flow and compressible properties with angle of repose 28.60°, Carr's compressibility of 21.30% and Hausner's quotient of 1.27. The tablets were hard, but did not disintegrate after one hour. Furthermore, only 52.5% of paracetamol was released after one hour. The drug release profile followed zero order kinetics. Tablets prepared with bombax gum have the potential to deliver drugs in a controlled manner over a prolonged period at a constant rate.