Guaianolides from Tanacetopsis karataviensis (Kovalevsk.) Kovalevsk.

In continuation of our phytochemical study on the aerial part of Tanacetopsis karataviensis (Kovalevsk.) Kovalevsk, three new guaiane-type sesquiterpene lactones were isolated namely karatanolide (1), 11,13ß-dihydrokaratanolide (2) and 11,13α-dihydrokaratanolide (3), in addition to the two known sesquiterpene lactones 1ß,10α-dihydroxyarglabin (4) and artefin (5). The structures of the isolated sesquiterpene lactones were elucidated by IR and NMR spectroscopy. Single crystal X-ray diffraction allowed to unambiguously confirm the structure of the isolated sesquiterpene lactones. Quantum chemical calculations of the guaianolides 1-3 suggested the existence of two conformations for the seven-membered cycle. All sesquiterpene lactones from Tanacetopsis karataviensis were isolated for the first time.

[Bioelectrical reactions on the surface of the mamma in the goat]. / Bioélektricheskie reaktsii na poverkhnosti molochnoi zhelezy kozy.

Spontaneous and evoked biopotentials were recorded on the mammary gland surface in goats. The biopotentials appear in the course of secretion during milk ejection as well as under electrical, mechanical and hormonal actions. They might be considered as adequate indices of secretion and ejection processes in the mammary gland.