Cost-effectiveness of shoulder arthroplasty for osteoarthritis and rotator cuff tear arthropathy. An economic analysis using real-world data.

INTRODUCTION: This study aimed to assess cost-effectiveness of shoulder arthroplasty for osteoarthritis (OA) and rotator cuff tear arthropathy (CTA) from the perspective of a publicly funded health care system using patient data, health utilities and costs from a real-world situation. HYPOTHESIS: Our hypothesis was that arthroplasty for OA is more cost-effective than for CTA. MATERIAL AND METHODS: We gathered a cohort of patients with 153 anatomic total shoulder arthroplasty (TSA) for OA and 107 reverse shoulder arthroplasty (RSA) for CTA between years 2016-2020 at a university hospital. Short-term (mean 2.8years) shoulder function, health utilities and costs were obtained from prospectively collected data, and a Markov cohort simulation was carried out to assess lifetime cost-utility. The primary outcome measures were change in 15D score to calculate gain in quality-adjusted life years (QALYs) and change in Western Ontario osteoarthritis score of the shoulder (WOOS). RESULTS: Both TSA and RSA restored shoulder function well, WOOS improvement was 59.7 (95% CI: 56.2-63.2) and 55.8 (95% CI: 50.4-61.2), respectively. The cost/QALY gained was 20,846.82 € for TSA and 38,711.90 € for RSA. The cost-utility was not remarkable sensitive to costs, discounting of future costs or estimated revision rates. However, the cost-effectiveness was very sensitive to change in 15D health utility scores and thus QALY gain, especially for RSA patients. DISCUSSION: Shoulder arthroplasty restores shoulder function well in both OA and CTA. In health economic terms, RSA is less cost-effective than TSA in an everyday setting, mainly due to inferior improvement of health-related quality-of-life and reduced life expectancy of CTA patients. LEVEL OF EVIDENCE: III; case series.

Risk factors for complications after volar plate fixation of distal radial fractures.

This study assessed risk factors for complications after volar plate fixation of distal radial fractures. An assessment of electronic patient records from 2008 to 2016 identified 867 patients with a total of 881 distal radial fractures who underwent volar plating in our hospital. A total of 132 complications after volar plate fixation of distal radial fractures were observed (complication rate 15%). Surgery performed by a low-volume surgeon and patient age less than 40 years were the most important risk factors for plate-related complications. In logistic regression analysis, operation performed by a low-volume surgeon and patient age less than 40 years were independent predictors of plate-related complications. Patient age less than 40 years and low-volume surgeon were also found to be independent risk factors for plate-related secondary operations. Surgical delay had no effect on the complication rate. Level of evidence: IV.

Adherence to resuscitation guidelines during prehospital care of cardiac arrest patients.

OBJECTIVE: The impact of prehospital care after the return of spontaneous circulation in out-of-hospital cardiac arrest patients is not known. This study describes adherence to the resuscitation guidelines, factors associated with poor adherence and possible impact of prehospital postresuscitation care on the outcome of out-of-hospital cardiac arrest. METHODS: One hundred and fifty-seven Finnish out-of-hospital cardiac arrest patients hospitalized during 1 year, were analyzed retrospectively. Patient and arrest characteristics, prehospital postresuscitation care and survival to hospital discharge were analyzed using multivariate logistic regression. RESULTS: Forty percent of the patients received care accordant with the guidelines. Male sex (P=0.045), witnessed arrest (P=0.031), initial ventricular fibrillation/ventricular tachycardia rhythm (P=0.007) and the presence of an emergency physician (P=0.017) were associated with care in line with the current guidelines. In multivariate logistic regression analysis, age over median (odds ratio=3.6, 95% confidence interval 1.5-8.6), nonventricular fibrillation/ventricular tachycardia initial rhythm (odds ratio=4.0, 95% confidence interval 1.6-9.8), administration of adrenaline (odds ratio=7.0, 95% confidence interval 2.3-21.4) and unsatisfactory prehospital postresuscitation care (odds ratio=2.5, 95% confidence interval 1.1-6.3) were associated with a failure to survive up to hospital discharge. CONCLUSIONS: Less than 50% of out-of-hospital cardiac arrest patients received prehospital postresuscitation care compatible with the current guidelines. Markers of poor prognosis were associated with unsatisfactory care, which in turn was more frequent among the patients who did not survive to hospital discharge. The importance of the guidelines should be highlighted in the future.