RESUMO
The objectives of the 'Task Force on Catastrophic Antiphospholipid Syndrome (APS) and Non-criteria APS Manifestations' were to assess the clinical utility of the international consensus statement on classification criteria and treatment guidelines for the catastrophic APS, to identify and grade the studies that analyse the relationship between the antiphospholipid antibodies and the non-criteria APS manifestations and to present the current evidence regarding the accuracy of these non-criteria APS manifestations for the detection of patients with APS. This article summarizes the studies analysed on the catastrophic APS, APS nephropathy and heart valve lesions, and presents the recommendations elaborated by the Task Force after this analysis.
Assuntos
Síndrome Antifosfolipídica/complicações , Valvas Cardíacas/patologia , Nefropatias/etiologia , Comitês Consultivos , Anticorpos Antifosfolipídeos/efeitos adversos , Síndrome Antifosfolipídica/classificação , Síndrome Antifosfolipídica/patologia , Síndrome Antifosfolipídica/fisiopatologia , Congressos como Assunto , Consenso , Feminino , Guias como Assunto , Valvas Cardíacas/anormalidades , Humanos , Nefropatias/patologia , Nefropatias/fisiopatologia , Gravidez , TexasRESUMO
The objectives of the 'Task Force on Catastrophic Antiphospholipid Syndrome (APS) and Non-criteria APS Manifestations' were to assess the clinical utility of the international consensus statement on classification criteria and treatment guidelines for the catastrophic APS, to identify and grade the studies that analyze the relationship between the antiphospholipid antibodies and the non-criteria APS manifestations, and to present the current evidence regarding the accuracy of these non-criteria APS manifestations for the detection of patients with APS. This article summarizes the studies analyzed on thrombocytopenia and skin manifestations, and presents the recommendations elaborated by the Task Force after this analysis.