RESUMO
During a period of 13 years, 84 patients underwent total cystectomy for transitional cell carcinoma of the bladder. The corrected 5-year survival rate was 58%. The operative mortality was 5 patients (6%). The 5-year survival rate of 42 patients who were treated by surgery alone was 53%, whereas that of 42 patients who received preoperative radiation of 30-40 Gy was 65%. The prognoses of the patients were dependent on the histological differentiation and the extent of the primary tumour within each treatment group.
Assuntos
Carcinoma de Células de Transição/terapia , Cistectomia , Neoplasias da Bexiga Urinária/terapia , Adulto , Idoso , Carcinoma de Células de Transição/mortalidade , Carcinoma de Células de Transição/secundário , Terapia Combinada , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Dosagem Radioterapêutica , Taxa de Sobrevida , Neoplasias da Bexiga Urinária/mortalidadeRESUMO
The response to radiation treatment was studied in 110 patients with head and neck cancer with a minimum follow-up of two years. If the tumour had disappeared by the mid-point of treatment (3000 rad), a significantly more favourable prognosis was found in early (T1-2N0) tumours. On the other hand, whether these tumours had disappeared or were persisting at the end of treatment, there was no difference in the recurrence during the observation time of two years. In advanced tumours there was no significant relationship between disappearance by the mid-point of treatment and recurrence up to two years. But when an advanced tumour had disappeared at the end of treatment, the prognosis was significantly more favourable. The unpredictability and often impossibility of judging the prognosis in individual cases encourages the authors to stress the importance of executing the original individual surgical plan irrespective of radiation response.
Assuntos
Carcinoma de Células Escamosas/radioterapia , Neoplasias de Cabeça e Pescoço/radioterapia , Carcinoma de Células Escamosas/patologia , Seguimentos , Neoplasias de Cabeça e Pescoço/patologia , Humanos , Neoplasias Laríngeas/patologia , Neoplasias Laríngeas/radioterapia , Recidiva Local de Neoplasia , Estadiamento de Neoplasias , PrognósticoRESUMO
66 cases treated with external megavoltage irradiation for various malignant diseases in the abdomen are presented 26 patients (39%) had radiation reactions during and immediately after the treatment. Late complications at least two months after the treatment appeared in 15 patients (23%). The relatively low frequency of intestinal disturbances induced by radiotherapy in the present series may have been caused by the low weekly dose in the abdomen and the practise of a split-course interval in the midst of treatment.
