[The actualization of heteronomous monosynaptic connections of IA afferents in the muscle motor centers of the human hand]. / Aktualizatsiia geteronimnykh monosinapticheskikh sviazei afferentov IA v dvigatel'nykh tsentrakh myshts kisti cheloveka.

Reflex excitability of spinal centers of hand muscles was examined in normal subjects and patients with traumatic lesion of forearm nerves. Central and peripheral muscle responses were evoked by stimulation of homonymous and heteronymous nerves. Patients with median and/or ulnar nerve lesion showed the heteronymous abductor pollicis brevis and abductor digit minimi H-responses. The cause of appearance of heteronymous responses is supposed to be actualization of latent heteronymous monosynaptic connections following traumatic lesion and afferent deprivation. It seems obvious that activation of heteronymous pathways corresponds to the process in afferent system known as "revitalization" of median-to-ulnar anastomoses after damage.

[The pathogenesis of combined maxillocerebral trauma]. / O patogeneze sochetannoi cheliustno-mozgovoi travmy.

Study of the systemic and regional blood pressure in various parts of the maxillofacial area and of microcirculation in tissues and fundus oculi in patients with maxillofacial injuries showed that such traumas involve brain injuries in 100% of cases and are therefore combined. The authors emphasize that this patient population is to be treated for brain injuries.

[The effect of multimodal pathogenetic therapy on microcirculatory function in combined craniocerebral trauma]. / Vliianie kompleksnoi patogeneticheskoi terapii na sostoianie mikrotsirkuliatsii pri sochetannoi cheliustno-mozgovoi travme.

It is known that severe combined maxillocranial trauma causes impairment of microcirculatory vessels of bulbar conjunctiva as well as changes of local (cervical) and systemic blood flow, prevailing on the side of injury. New trigeminosympathetic regional block was used to produce chemical neurotomy of sympathetic and parasympathetic portions of autonomous nervous system in the neck. This blockade induced positive changes of minute CBF and microcirculation of CNS and facial area. Modified trigeminal sympathetic regional blockade along with intravenous infusion of dimephosphone improves both microcirculation and reparative-proliferative process in impacted area.

[The microcirculatory bed and the blood rheological properties in the acute period of severe craniocerebral trauma]. / Mikrotsirkuliatornoe ruslo i reologicheskie svoistva krovi v ostrom periode tiazheloi cherepno-mozgovoi travmy.

The microcirculatory channel of the bulbo-conjunctival vessels and the blood rheological properties were studied in 128 patients in the acute period of a severe craniocerebral trauma. Disorders of microcirculation and hemorheology were detected in the early periods, reached maximum by the 3rd-7th day and reflected the condition of cerebral circulation. Progressive growth of blood fibrinogen concentration, development of intravascular aggregation of red cells and their stasis, slow and bead-like blood flow, drastic dilatation of venules and capillaries with reduction of their number and absence of response to vasoactive agents are signs of an unfavourable outcome of traumatic disease.

[Role of kinins in the pathogenesis of craniocerebral injury and the validation of corrective antiproteolytic therapy]. / Rol' kininov v patogeneze cherepno-mozgovoi travmy i obosnovanie korrigiruiushchei antiproteoliticheskoi terapii.

The role of the kinin system in the development of extra- and intracerebral complications in the acute period of severe craniocerebral trauma was studied from complex clinical and biochemical examination. The authors substantiate the expediency of applying corrective antiproteolytic therapy, in which case the predominant trend of its action--inhibition of kinin production in the vascular bed or on the tissue level--must be taken into account. The time, duration, and methods of Contrykal administration were developed.

[Transcapillary filtration of electrolytes in the brain after craniocerebral injuries]. / Transkapilliarnaia fil'tratsiia élektrolitov v golovnom mozge posle cherepno-mozgovoi travmy.

A new method was used to determine the value and direction of electrolyte filtration through the walls of capillaries in the brain in patients with craniocerebral injury. It was found that the period of the development of brain edema coincided in time with the prevalence of the processes of sodium, calcium, and fluid escape from the cerebral vessels into the cerebral tissue. The movement of potassium through the capillary wall was counter-current to that of sodium filtration in most cases. Transcapillary filtration of electrolytes in patients with craniocerebral injury during the posttraumatic period was characterized by recurrent changes in the direction of filtration. Electrolytes (sodium, potassium, and calcium) possess their own, often independent of one another, mechanisms of transfer through the membranes of the histohematic barriers.