RESUMO
Hibernomas are uncommon benign soft tissue tumours mimicking brown fat. The most common anatomic locations include the neck, axilla, mediastinum, periaortic and perirenal zones. Intrathoracic and in particular pleural locations are exceptional. We report two cases of intrathoracic hibernoma with pleural involvement treated by surgical resection.
Assuntos
Lipoma/diagnóstico , Lipoma/patologia , Neoplasias Pleurais/diagnóstico , Neoplasias Pleurais/patologia , Toracoscopia , Adipócitos Marrons/patologia , Diagnóstico Diferencial , Intervalo Livre de Doença , Feminino , Humanos , Lipoma/cirurgia , Masculino , Neoplasias Pleurais/cirurgia , Tomografia por Emissão de Pósitrons , Radiografia Torácica , Testes de Função Respiratória , Neoplasias de Tecidos Moles/diagnóstico por imagem , Neoplasias de Tecidos Moles/patologia , Cavidade Torácica/cirurgia , Toracotomia , Tomografia Computadorizada por Raios X , Adulto JovemRESUMO
The case of a 56-year old male with an intra-abdominal metastasis from a primary lung cancer is presented. He was admitted for abdominal obstruction, toxic syndrome and paraumbilical pain. He had a previous history of squamous cell carcinoma of the right lung, for which he had undergone a right upper lobectomy in 1995, four years prior to the development of the abdominal obstruction. A debulking operation and bowel resection for the intestinal metastasis was performed. Eleven months after this operation the patient developed a recurrence: he underwent another debulking operation with resection of the sigmoid colon, jejunal segment and a small part of the bladder. The patient is alive and well 13 months after the initial operation. Intra-abdominal metastases of bronchial carcinoma may be observed with greater frequency, because of the improved survival of the patients with lung cancer. Metastatic small bowel carcinomas are rare and should be considered in the differential diagnosis of acute abdominal syndromes of patients with known history of the lung cancer. Bowel resection and debulking of the metastatic tumour mass give the best palliation and improve short-term survival.
Assuntos
Carcinoma de Células Escamosas/patologia , Neoplasias Intestinais/secundário , Neoplasias Pulmonares/patologia , Carcinoma de Células Escamosas/diagnóstico por imagem , Humanos , Neoplasias Intestinais/diagnóstico por imagem , Neoplasias Intestinais/cirurgia , Masculino , Pessoa de Meia-Idade , Tomografia Computadorizada por Raios XAssuntos
Adenoma , Lipoma , Neoplasias Primárias Múltiplas , Neoplasias do Timo , Neoplasias da Glândula Tireoide , Adenoma/diagnóstico por imagem , Adenoma/cirurgia , Adulto , Humanos , Lipoma/diagnóstico por imagem , Lipoma/cirurgia , Masculino , Neoplasias Primárias Múltiplas/diagnóstico por imagem , Neoplasias Primárias Múltiplas/cirurgia , Radiografia , Neoplasias do Timo/diagnóstico por imagem , Neoplasias do Timo/cirurgia , Neoplasias da Glândula Tireoide/diagnóstico por imagem , Neoplasias da Glândula Tireoide/cirurgiaRESUMO
Interruption of the aortic arch and hypoplastic left heart syndrome in the same patient is exceptional. In the combined collections of the Registry of Cardiovascular Disease (St. Paul, Minnesota, U.S.A.) and the Registry of Congenital Heart Defects of the Rijksuniversiteit Gent (Gent, Belgium) three specimens were found with this unusual combination. These cases are herein described and compared with four similar cases previously reported in the literature.
Assuntos
Aorta Torácica/anormalidades , Cardiopatias Congênitas/patologia , Síndrome do Coração Esquerdo Hipoplásico/patologia , Valva Mitral/patologia , Anormalidades Múltiplas/patologia , Aorta Torácica/patologia , Feminino , Doenças Fetais , Humanos , Recém-Nascido , MasculinoRESUMO
In two patients, women of 65 and 76 years old, colitis cystica profunda was diagnosed, a rare, benign disease of colon and rectum. In the first patient, radio-enteritis, in the second patient mucinous adenocarcinoma was diagnosed as well.
Assuntos
Colite/patologia , Adenocarcinoma Mucinoso/complicações , Adenocarcinoma Mucinoso/patologia , Idoso , Colite/diagnóstico , Colite/cirurgia , Colo/efeitos da radiação , Colonoscopia , Feminino , Humanos , Lesões por Radiação , Neoplasias do Colo Sigmoide/complicações , Neoplasias do Colo Sigmoide/patologiaRESUMO
Case report of a patient with a giant ovarian cyst. On the basis of literature data, surgery and histology problems, as well as oncological therapy are discussed.
Assuntos
Cistadenocarcinoma Mucinoso/cirurgia , Neoplasias Ovarianas/cirurgia , Quimioterapia Adjuvante , Cistadenocarcinoma Mucinoso/tratamento farmacológico , Cistadenocarcinoma Mucinoso/patologia , Feminino , Humanos , Pessoa de Meia-Idade , Neoplasias Ovarianas/tratamento farmacológico , Neoplasias Ovarianas/patologiaRESUMO
We report a case of leiomyomatosis that involved the small intestine and colon. On gross examination, the bowel wall was irregularly thickened at various levels. Histologically, the lesions were characterized by multifocal, diffuse tumor masses that were present in the muscular layers. These masses consisted of proliferating smooth-muscle cells that often surrounded prominent blood vessels. Cytologic atypia was not observed, and the mitotic count was low, illustrating the benign nature of the tumors. Findings from immunohistochemical analysis of the lesions were essentially negative; vimentin, cytokeratin, actin, desmin, and S100 stains showed no reactivity in the tumor cells, despite positive internal controls. By reviewing the literature, we found several reports on related lesions that occurred in the gastrointestinal tract; diffuse leiomyomatosis of the esophagus and the colon have been reported. We did not find any report on the small intestinal variant of the disease; therefore, it seemed useful to term this new localization as leiomyomatosis of the small intestine and colon.
Assuntos
Neoplasias do Colo/patologia , Neoplasias Intestinais/patologia , Intestino Delgado/patologia , Leiomioma/patologia , Neoplasias Primárias Múltiplas/patologia , Feminino , Humanos , Pessoa de Meia-IdadeRESUMO
We reviewed 25 patients with thymoma for clinical symptoms at presentation, X-ray findings and outcome. The tumours of all patients were classified using 3 different pathologic classification systems and each system was evaluated for its predictive power with respect to survival. The recent classification system by Müller-Hermelink allowed to distinguish thymomas with associated systemic syndromes from those without. However, no good prediction with respect to outcome could be made by any of the 3 systems.
Assuntos
Timoma/patologia , Timo/patologia , Neoplasias do Timo/patologia , Análise Atuarial , Terapia Combinada , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Valor Preditivo dos Testes , Análise de Sobrevida , Timoma/mortalidade , Timoma/terapia , Neoplasias do Timo/mortalidade , Neoplasias do Timo/terapia , Resultado do TratamentoRESUMO
Adamantinomas of long bones are rare primary malignant bone tumors. A case of a woman who died of pulmonary metastases of an adamantinoma of the tibia is presented. A unique feature of this case is the association with hypercalcemia. The association of hypercalcemia, hypophosphatemia, decreased parathyroid hormone levels and increased urinary cAMP excretion suggests a humorally mediated hypercalcemia. Histologic and ultrastructural analysis of the pulmonary metastases demonstrated that the tumor was composed of a heterogeneous cell population with mesenchymal and epithelial differentiation.
Assuntos
Neoplasias Ósseas/patologia , Hipercalcemia/etiologia , Neoplasias Pulmonares/secundário , Adulto , Neoplasias Ósseas/complicações , AMP Cíclico/sangue , Feminino , Humanos , Hipercalcemia/sangue , Pulmão/patologia , Neoplasias Pulmonares/complicações , Neoplasias Pulmonares/diagnóstico por imagem , Neoplasias Pulmonares/patologia , Fosfatos/sangue , RadiografiaRESUMO
Ossification of the posterior longitudinal ligament is rare among Caucasians. We describe a new case with lethal outcome and we discuss the radiographic and pathologic findings. Posterior longitudinal ligament ossification is a benign disease in most cases, but it may cause severe myelopathy due to spinal stenosis. Diagnosis may be suspected or made on lateral views of the cervical spine and ascertained by CT.
Assuntos
Vértebras Cervicais/diagnóstico por imagem , Ligamentos/diagnóstico por imagem , Ossificação Heterotópica/diagnóstico por imagem , Idoso , Feminino , Humanos , Ligamentos/patologia , RadiografiaRESUMO
The clinical history of a 60-year-old woman suffering from chronic lymphocytic leukemia with sudden deterioration and death is reported. The postmortem macroscopic and microscopic findings included pulmonary aspergillosis and pulmonary zygomycosis (mucormycosis). Hematogenous dissemination of the zygomycete causing cardiac zygomycosis, cerebral infarcts due to vascular occlusion by hyphae, and thrombosis of the major hepatic veins (Budd-Chiari syndrome) with submassive necrosis of the right liver lobe were also observed. To our knowledge, this is the second report dealing with occlusion of the hepatic veins caused by a fungus and the first study reporting the Budd-Chiari syndrome due to a mold of the subclass Zygomycetes.
Assuntos
Síndrome de Budd-Chiari/etiologia , Mucormicose/complicações , Síndrome de Budd-Chiari/patologia , Feminino , Veias Hepáticas/patologia , Humanos , Fígado/patologia , Linfoma não Hodgkin/complicações , Pessoa de Meia-Idade , Mucormicose/patologiaRESUMO
Thrombosis of a giant aneurysm of the basilar artery appears on computed tomographic scan as a well-delineated, prepontine, hyperdense mass.