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1.
Arch Mal Coeur Vaiss ; 98(5): 557-60, 2005 May.
Artigo em Francês | MEDLINE | ID: mdl-15966608

RESUMO

In patients successfully operated for coarctation of the aorta, the prevalence of hypertension is higher than that observed in the general population although the exact mechanism is not known. The hypothesis of increased arterial rigidity despite satisfactory correction of the coarctation has been proposed. The authors undertook 24 hour ambulatory blood pressure monitoring coupled with measurement of the QKD interval (pulse wave velocity) in order to evaluate the rigidity of the large arteries. These results were compared with those obtained in control patients paired with respect to gender, age, height and weight. Twenty-six patients with an average age of 14.5 +/- 2.9 years were included (age at time of surgery 6.3 +/- 3.7 years). The statistical data confirmed a higher systolic blood pressure (p<0.05) in the operated patients compared with controls. The results confirm the hypothesis of increased residual arterial rigidity in children operated for coarctation of the aorta which could predispose to secondary hypertension, especially on effort. In the long term, this could be an unquestionable cardiovascular risk factor explaining the increased cardiovascular morbid-mortality compared with the general population.


Assuntos
Coartação Aórtica/complicações , Coartação Aórtica/cirurgia , Artérias/patologia , Hipertensão/etiologia , Adolescente , Monitorização Ambulatorial da Pressão Arterial , Estudos de Casos e Controles , Pré-Escolar , Feminino , Humanos , Masculino , Fatores de Risco , Resistência Vascular
2.
Arch Mal Coeur Vaiss ; 94(5): 499-503, 2001 May.
Artigo em Francês | MEDLINE | ID: mdl-11434019

RESUMO

An anomalous left coronary artery arising from the right sinus of Valsalva with a trajectory between the aorta and the main pulmonary artery is a rare isolated congenital anomaly carrying a high risk of sudden death and of acute myocardial ischaemia, especially in children and young adults in a context of exercise. It is usually a post-mortem finding. The authors report the rare case of a 12 year old child who suffered acute myocardial infarction on exercise due to this condition. The diagnosis was made in the acute phase by echocardiography. Surgical correction was performed as this is the only means of prevention of sudden death of an ischaemic recurrence. Effort syndromes in children or young adults should lead to a request for echocardiographic examination to exclude the diagnosis in a non-invasive manner as well as those of hypertrophic cardiomyopathy or congenital aortic stenosis.


Assuntos
Anomalias dos Vasos Coronários/complicações , Anomalias dos Vasos Coronários/cirurgia , Infarto do Miocárdio/etiologia , Seio Aórtico/anormalidades , Criança , Morte Súbita Cardíaca/prevenção & controle , Ecocardiografia , Eletrocardiografia , Exercício Físico , Feminino , Humanos , Revascularização Miocárdica , Fatores de Risco
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