1.
Org Biomol Chem
; 12(24): 4211-7, 2014 Jun 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24838529
RESUMO
Four new enantiomerically and diastereomerically pure hemicryptophane hosts (M-SSS-2/P-SSS-2 and M-RRR-2/P-RRR-2 pairs) were designed for the recognition of sugar derivatives. Their absolute configuration was determined from the circular dichroism spectra and DFT calculations. The host molecules were then used for the stereoselective recognition of glucopyranosides. Binding constants were obtained from (1)H NMR titration experiments showing an increase of affinity for this class of receptors, associated with an improved diastereo- and enantio-differentiation.
Assuntos
Glucosídeos/química , Compostos Policíclicos/química , Dicroísmo Circular , Cinética , Modelos Moleculares , Conformação Molecular , Espectroscopia de Prótons por Ressonância Magnética , Teoria Quântica , Estereoisomerismo
2.
J Am Chem Soc
; 129(42): 12614-5, 2007 Oct 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17914822