Precision of fit and clinical evaluation of all-ceramic full restorations followed between 0.5 and 5 years.

Currently CAD-CAM systems are rapidly gaining importance in dental practice as some of their products aim to combine aesthetics with strength and are free of metals. This study reports on the crown adaptation, marginal fit and clinical behaviour of 300 all-ceramic full coverage restorations (Procera, Gothenburg, Sweden) placed in one clinical centre and followed up to 5 years. The marginal fit and coping adaptation before and after luting was determined by direct measurement as well as after sectioning in a laboratory study. Three hundred all-ceram restorations were installed in 165 patients between 1994 and 1998. Before the end of 2000, patients were recalled to assess their restorations, using the California Dental Association quality evaluation index, their own appreciation, as well as the reaction towards the periodontium. The in vitro data revealed a mean marginal adaptation of 30 microm, before and after luting of the Al(2)0(3)-coping onto the tooth. However, at the deepest part of the chamfer, the distance increased to 135 microm. In the clinical study only one restoration fractured, while in 6% small porcelain infractions occurred. After polishing the latter, no persistent patient complaints remained. At the last recall visit 1.8% of the margins were rated unacceptable. Dentists rated 72 and 78% of the restorations excellent for surface, colour and anatomic form respectively. Eighty-seven per cent of the patients rated their restorations more than 7/10 on an ordered analogue scale for aesthetics as well as for function.

Intradermal skin testing in the investigation of suspected anaphylactic reactions during anaesthesia--a retrospective survey.

An anaphylactic reaction is a rare, but severe anaesthetic complication. In this retrospective survey we report on patients with a severe suspected anaphylactic reaction during anaesthesia and the investigation with intradermal skin testing of these suspected anaphylactic reactions. In the patients with an anaphylactic reaction to neuromuscular blocking drugs, the subsequent anaesthetic history was examined. Sixty-five patients suffered a suspected anaphylactic reaction between 1976 and 2001. In 47 patients skin testing was performed and 43 of these patients had positive skin tests: neuromuscular blockings drugs and succinylcholine more specifically, were the most frequently incriminated drugs. After the anaphylactic reaction 19 patients had surgery on 26 occasions with the use of a skin-test-negative neuromuscular blocking drug; no problems occurred. Skin testing proved to be a reliable tool to investigate suspected anaphylactic reactions during anaesthesia and to guide the future use of neuromuscular blocking drugs.

Influence of maternal position during epidural labor analgesia.

The influence of maternal position on the spread of local anesthetics in low concentration has not been well examined during epidural analgesia for labor. This study was designed to investigate the differences in sensory block, pain relief and incidence of supine hypotensive syndrome between parturients in the left lateral position and in a modified supine position. Sixty-seven parturients were randomly assigned to lie either in the left lateral position (n = 34) or in a modified supine position (n = 33), and received 0.125% bupivacaine 10 mL with epinephrine 1:800000 and sufentanil 7.5 microg. At 20 min parturients in the modified supine position turned to the left lateral position and a second investigator, unaware of the initial position, measured the extent of the sensory block at 20 and 30 min and just before a second epidural injection was requested. More dermatomes were blocked on the dependent side when the dose was injected in the left lateral position (at 20 and 30 min: P < 0.05; before the second epidural injection: P < 0.0005). In the modified supine position the incidence of bilaterally blocked dermatomes T10-L1 was greater at 20 and 30 min (P < 0.05) and the pain on a visual analogue scale was better at 30 min (P < 0.05). Three parturients in the modified supine position had signs and symptoms of supine hypotensive syndrome. We conclude that injecting in the modified supine position results in a more equal spread of local anesthetic and better pain relief.

Uptake of desflurane and isoflurane during closed-circuit anesthesia with spontaneous and controlled mechanical ventilation.

Although theoretical models predict uptake of inhaled anesthetics during closed-circuit anesthesia (CCA), clinical data for most anesthetics are conflicting or non-existent. In addition, the effects of patient characteristics and mode of ventilation on anesthetic uptake are unclear. Forty-one ASA physical status I or II adult patients undergoing a variety of 1-1.5 h surgical procedures were randomly allocated to receive CCA with desflurane or isoflurane with ventilation being either spontaneous or controlled. An end-expired anesthetic concentration of 1.3 minimum alveolar anesthetic concentration (MAC) was maintained by continuous injection of the liquid anesthetic into the circuit using a syringe pump. After an initial 4-min wash-in period, uptake during the first hour of CCA was nearly constant. Uptake was the same whether ventilation was spontaneous or controlled. Patient characteristics (age, height, weight, weight3/4, and body surface area) were comparable between groups and did not correlate with uptake. The virtually constant uptake after wash-in of desflurane and isoflurane contrasts with the square root of time model of Lowe and Ernst. These findings may greatly simplify CCA.

Sore throat with the laryngeal mask: does the lubricant matter?

In daily anesthetic practice, the insertion of a Laryngeal Mask--airway is facilitated by means of a lubricant. Many different products are in widespread clinical use, according to personal preference or what's in or on the anesthesia trolley. This study compares four different lubricants: Xylocaine 10% spray, Silkospray, Endosgel and water. When comparing the ease of insertion of the Laryngeal Mask, the genuine lubricants proved to be superior to water. However, no single lubricant was associated with a statistically significant lower incidence of postoperative sore throat.

Motor blockade during epidural anesthesia.

The effects of lumbar epidural anesthesia (LEA) on a previously described test of function of the rectus abdominalis muscle (the RAM-test) were compared with the effects of LEA on the Bromage test of muscle power in the hips and legs in 20 women having elective cesarean sections under LEA using 0.5% bupivacaine with epinephrine 1:200,000. The results showed no statistically significant correlation between the two tests. We conclude that zones of differential somatic motor blockade are present during LEA and that in obstetrics the RAM-test is the more appropriate test for evaluating the effects of LEA on somatic motor function. Use of the RAM-test is suggested in situations where one is interested in motor function of the abdominal wall muscles under LEA.

Bupivacaine, 0.125 per cent, in obstetric epidural analgesia: experience in three thousand cases.

Bupivacaine, 0.125 per cent, with epinephrine, 1:800,000, was administered to 3,000 women in labor. Administration was in the lumbar epidural space for the purpose of achieving satisfactory analgesia with minimal or no motor paralysis. The usual initial dose of 12.5 mg (mean 13 +/- 2 SD) resulted in good sensory analgesia in 83 per cent of the patients and lasted for about and hour (mean 58 +/- 16 min). The mean total dose used for labor and delivery was 55 +/- 20 mg and the mean dose per hour 23 +/- 13 mg. Satisfactory analgesia for labor and delivery was obtained in 92 per cent of the patients, and in 66 per cent there was no discernible motor blockade. In the 3,000 patients, there was no adverse reaction to bupivacaine or epinephrine. No patient had a total spinal block or neurologic sequelae, and no neonatal depression could be attributed to the anesthetic.