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1.
J Med Imaging Radiat Oncol ; 68(1): 26-32, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-37654031

RESUMO

INTRODUCTION: Timely recognition of dysplastic hip morphology is critical to facilitate appropriate management before significant joint damage has developed. It is likely that radiologist under reporting contributes to delays in diagnosis. This study aimed to assess how often adult hip dysplasia goes undetected in radiological reports and to identify clinical and radiological variables that impact the likelihood of detection of dysplasia by radiologists. METHODS: Referral details and radiology reports of patients who underwent periacetabular osteotomy by a single surgeon for symptomatic hip dysplasia between 1 January 2016 and 30 June 2020 were reviewed. Four assessors measured the lateral centre edge angle from the pelvic radiograph performed at time of referral. Film quality and other radiographic parameters were also assessed. RESULTS: Sixty-eight patients were included, 84% were female and the median age was 28.1 years. Dysplasia was not documented in the radiology report in 49% of cases. Dysplasia was more likely to be reported with no history of injury, an aspherical femoral head, lower lateral centre edge angle, higher acetabular index, increased femoral head shaft angle, higher femoro-epiphyseal acetabular roof index, or if there was disruption of Shenton's line, with the first three variables being independent predictors of radiologist detection. CONCLUSION: Hip dysplasia should be considered in all adolescents/young adults presenting with hip pain. Causes of radiologist under reporting are likely multifactorial. Clinical information can cause cognitive biases and result in selective looking. A systematic approach to pelvis radiographs should include assessment of acetabular coverage and active search for evidence of femoral head migration.


Assuntos
Luxação Congênita de Quadril , Luxação do Quadril , Radiologia , Adulto Jovem , Adolescente , Humanos , Feminino , Adulto , Masculino , Luxação do Quadril/diagnóstico por imagem , Estudos Retrospectivos , Luxação Congênita de Quadril/diagnóstico por imagem , Luxação Congênita de Quadril/cirurgia , Acetábulo/diagnóstico por imagem
2.
Pediatrics ; 137(3): e20153542, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26908702

RESUMO

BACKGROUND: Legg-Calvé-Perthes disease (LCPD) is an idiopathic avascular necrosis of the femoral head. Its etiology is poorly understood, although previous studies have implicated low birth weight and possible genetic determinants. The aim of this study was to identify potential birth weight and genetic associations with LCPD. METHODS: We extracted all twin pairs from the Danish Twin Registry (DTR) in which at least 1 individual had LCPD. The DTR captures every twin pair born alive in Denmark, and those with LCPD were identified by using health record linkage. Probanwise concordance was calculated to describe the likelihood that any given individual had LCPD if their co-twin was also diagnosed. RESULTS: There were 81 twin pairs: 10 monozygotic, 51 dizygotic, and 20 unclassified (unknown zygosity [UZ]). There was no association between birth weight and being the affected co-twin. Four pairs (2 dizygotic and 2 UZ) were concordant for LCPD, which is greater than would be expected assuming no familial aggregation. There were no concordant monozygotic twin pairs. The overall probandwise concordance was 0.09 (95% confidence interval [CI]: 0.01-0.18): 0.00 for the monozygotic, 0.08 (95% CI: 0.00-0.18) for the dizygotic, and 0.18 (95% CI: 0.00-0.40) for the UZ twin pairs. CONCLUSIONS: This study found evidence of familial clustering in LCPD but did not show a genetic component. The absolute risk that a co-twin of an affected individual will develop LCPD is low, even in the case of monozygotic twin pairs.


Assuntos
Predisposição Genética para Doença , Doença de Legg-Calve-Perthes/genética , Gêmeos Dizigóticos/genética , Gêmeos Monozigóticos/genética , Criança , Pré-Escolar , Dinamarca/epidemiologia , Doenças em Gêmeos/genética , Feminino , Humanos , Incidência , Doença de Legg-Calve-Perthes/epidemiologia , Masculino , Estudos Retrospectivos
3.
JBJS Case Connect ; 5(4): e106, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-29252812

RESUMO

CASE: A twelve-year-old slender white girl underwent pinning of a slipped capital femoral epiphysis (SCFE) on both the right and left sides. The bilateral nature of the disease and her slender build prompted consideration of an underlying predisposition. She was referred for medical evaluation, which resulted in the identification of medullary thyroid carcinoma. CONCLUSION: This report highlights the importance of recognizing atypical presentations of SCFE and the necessity for investigation of associated comorbid diagnoses. As with this case, atypical SCFE may represent the sentinel event leading to identification of underlying systemic illness and therefore may present an opportunity for early intervention.

4.
J Bone Joint Surg Am ; 96(13): 1073-1079, 2014 Jul 02.
Artigo em Inglês | MEDLINE | ID: mdl-24990972

RESUMO

BACKGROUND: The rate of Achilles tendon ruptures is increasing, but there is a lack of consensus on treatment of acute injuries. The purpose of this trial was to compare outcomes of weight-bearing casts with those of traditional casts in the treatment of acute Achilles tendon ruptures. METHODS: Eighty-four patients with an acute Achilles tendon rupture were recruited over a two-year period. Patients were randomized to be treated with either a weight-bearing cast with a Böhler iron or a non-weight-bearing cast for eight weeks. Patients underwent muscle dynamometry testing at six months, with additional follow-up at one and two years. The primary outcomes that were assessed were the rerupture rate and the time taken to return to work. Secondary outcomes included return to sports, ankle pain and stiffness, footwear restrictions, and patient satisfaction. RESULTS: There were no significant differences between groups with regard to patient demographics or activity levels prior to treatment. At the time of follow-up at two years, one (3%) of the thirty-seven patients in the weight-bearing group and two (5%) of the thirty-seven in the non-weight-bearing group had sustained a rerupture (p = 0.62). The patients in the weight-bearing group experienced less subjective stiffness at one year. There were no significant differences in time taken to return to work, Leppilahti scores, patient satisfaction, pain, or return to sports between the groups. CONCLUSIONS: Use of weight-bearing casts for the nonoperative treatment of Achilles tendon ruptures appears to offer outcomes that are at least equivalent to those of non-weight-bearing casts. The overall rerupture rate in this study was low, supporting the continued use of initial nonoperative management for the treatment of acute Achilles tendon ruptures. LEVELS OF EVIDENCE: Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.


Assuntos
Tendão do Calcâneo/lesões , Traumatismos dos Tendões/terapia , Suporte de Carga/fisiologia , Adulto , Traumatismos em Atletas/terapia , Feminino , Humanos , Masculino , Nova Zelândia , Satisfação do Paciente , Recuperação de Função Fisiológica , Ruptura/terapia , Resultado do Tratamento
5.
J Clin Neurosci ; 21(5): 880-2, 2014 May.
Artigo em Inglês | MEDLINE | ID: mdl-24291484

RESUMO

Bleeding is the most important complication of treatment with intravenous tissue plasminogen activator for acute ischemic stroke. Neurologists are familiar with intracranial hemorrhage, the most feared site for bleeding following thrombolysis, but extracranial bleeding can also occur resulting in substantial morbidity and mortality. We describe an 88-year-old woman with an acute stroke who developed bleeding into the left arm complicated by hemodynamic instability and compartment syndrome following intravenous thrombolysis. The patient was treated conservatively in view of the risks associated with fasciotomy and her other medical comorbidities.


Assuntos
Braço/patologia , Síndromes Compartimentais/induzido quimicamente , Síndromes Compartimentais/diagnóstico , Acidente Vascular Cerebral/tratamento farmacológico , Terapia Trombolítica/efeitos adversos , Idoso de 80 Anos ou mais , Feminino , Humanos , Acidente Vascular Cerebral/diagnóstico
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