1.
Comb Chem High Throughput Screen
; 6(8): 777-87, 2003 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-14683483
RESUMO
The post-genomic era is revolutionizing the drug discovery process. The new challenges in the identification of therapeutic targets require efficient technological tools in order to be properly addressed. Label-free detection systems use proteins or ligands coupled to materials of which the physical properties are measurably modified upon specific interactions. Among the label-free systems currently available, the use of metal nanocolloids offers enhanced throughput and flexibility for real-time biomolecular recognition monitoring at a reasonable cost.
Assuntos
Técnicas Biossensoriais/métodos , Coloides/química , Metais Pesados/química , Humanos , Ligantes , Nanotecnologia , Ressonância de Plasmônio de Superfície
2.
Clin Chem
; 46(12): 2000-3, 2000 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-11106337