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Parasitol Res ; 118(3): 733-742, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-30671730

RESUMO

Aedes aegypti and Ae. albopictus are key vectors in the spread of arboviruses such as dengue, chikungunya, yellow fever, and Zika. Triatoma rubrofasciata is an "assassin bug" whose populations and association with humans have dramatically increased and may represent a serious health concern. Control of insect vectors is a logical course of action to prevent the spread of these insect-borne infections. This work presents the leaf essential oil composition, mosquito larvicidal activities, and insect-repellent activity of Severinia monophylla. The essential oil of S. monophylla from Vietnam was obtained by hydrodistillation and analyzed by gas chromatography and mass spectrometry. The major components were sabinene, ß-caryophyllene, bicyclogermacrene, germacrene D, (E)-nerolidol, globulol, and linalool. The leaf essential oil showed remarkable larvicidal activity against Ae. aegypti with LC50 (48 h) of 7.1 µg/mL and Ae. albopictus with LC50 (48 h) of 36 µg/mL. The essential oil also showed repellent activity on T. rubrofasciata at a concentration of 0.5%.


Assuntos
Aedes/efeitos dos fármacos , Dengue/prevenção & controle , Repelentes de Insetos/farmacologia , Inseticidas/farmacologia , Óleos Voláteis/farmacologia , Rutaceae/química , Triatoma/efeitos dos fármacos , Aedes/parasitologia , Animais , Dengue/transmissão , Cromatografia Gasosa-Espectrometria de Massas , Humanos , Repelentes de Insetos/química , Inseticidas/química , Espectrometria de Massas , Controle de Mosquitos , Mosquitos Vetores/efeitos dos fármacos , Mosquitos Vetores/parasitologia , Óleos Voláteis/química , Folhas de Planta/química , Óleos de Plantas/química , Óleos de Plantas/farmacologia , Terpenos/química , Terpenos/farmacologia , Vietnã
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