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Surv Ophthalmol ; 57(3): 284-91, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-21855953

RESUMO

A 55-year-old immunocompetent man presented with headache, nausea, progressive bilateral upper lid ptosis, and diplopia. Examination showed bilateral asymmetric upper lid ptosis with limited adduction and elevation of both eyes. Cranial magnetic resonance imaging revealed enhancing intra-axial and extra-axial midbrain lesions. Blood and cerebrospinal fluid were positive for cryptococcal antigen and cerebrospinal fluid fungal cultures grew Cryptococcus neoformans. Treatment with liposomal amphotericin B and flucytosine resulted in complete resolution of his neurological deficits and lesions on neuroimaging. Patients with cryptococcal meningitis may rarely present with bilateral cranial nerve III dysfunction.


Assuntos
Blefaroptose/etiologia , Cryptococcus neoformans/isolamento & purificação , Diplopia/etiologia , Meningite Criptocócica/complicações , Doenças do Nervo Oculomotor/etiologia , Encefalopatias/diagnóstico , Diagnóstico Diferencial , Humanos , Imageamento por Ressonância Magnética , Masculino , Meningite Criptocócica/diagnóstico , Pessoa de Meia-Idade , Miastenia Gravis/diagnóstico
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