RESUMO
A post-mortem histological examination of the eyes of a case of primary hyperoxaluria revealed the presence of crystals in the ciliary processes and at the level of the retinal pigment epithelium. The crystallography study demonstrated that it consisted of wewhellite. The ocular lesions are compared with those found by other authors in primary hyperoxaluria, after prolonged methoxyflurane anaesthesia, after experimental administration of dibutyloxalic acid or naphthalene, and in the human retina in longstanding detachments. Most of the factors which give rise to the presence in the eye of oxalate and its selective precipitation in the midst of certain ocular tissues remain hypothetical. The retinal lesions observed in primary hyperoxaluria appear to be pathognomonic for hyperoxalaemia.
Assuntos
Manifestações Oculares , Olho/ultraestrutura , Erros Inatos do Metabolismo/complicações , Oxalatos/urina , Adulto , Animais , Corpo Ciliar/ultraestrutura , Microanálise por Sonda Eletrônica , Humanos , Corpos de Inclusão/ultraestrutura , Masculino , Erros Inatos do Metabolismo/patologia , Metoxiflurano/efeitos adversos , Microscopia Eletrônica de Varredura , Microscopia de Polarização , Naftalenos/farmacologia , Oxalatos/metabolismo , Epitélio Pigmentado Ocular/ultraestrutura , Coelhos , Descolamento Retiniano/etiologia , Difração de Raios XRESUMO
Complete bilateral ureteric replacement by silicone prosthesis is described in a patient suffering from retroperitoneal involvement from prostatic carcinoma. Immediate and long-term results were very satisfactory from a functional and social point of view and encourage consideration of this new surgical procedure in certain forms of ureteric obstruction.
