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Pediatr Endocrinol Rev ; 11(1): 34-43, 2013 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-24079077

RESUMO

Studies have reported high adiponectin levels in children with type 1 diabetes mellitus (T1DM). Adiponectin has been found to have anti-atherogenic action and other protective functions. We wanted to estimate adiponectin level in south Indian T1DM children and compare it with that of non-diabetic children and study its correlation with anthropometry and glycemic status. Sixty children with T1DM and forty non-diabetic children of age less than 15 years were analysed. Mean adiponectin level was higher in T1DM group than in non diabetic group (p < 0.001) irrespective of the age group or sex. Negative correlation was observed between SFT- triceps and adiponectin in diabetic and control group. Multiple regression coefficient analysis of various parameters showed SFT- triceps as a statistically significant predictor of adiponectin level (p = 0.001). We conclude that, children with T1DM had higher adiponectin level than non-diabetic children. Low SFT- triceps measuremet may be a predictor of higher adiponectin level.


Assuntos
Adiponectina/sangue , Antropometria , Glicemia/metabolismo , Diabetes Mellitus Tipo 1/metabolismo , Índice Glicêmico/fisiologia , Adiposidade/fisiologia , Índice de Massa Corporal , Criança , Pré-Escolar , Estudos Transversais , Diabetes Mellitus Tipo 1/tratamento farmacológico , Feminino , Humanos , Hipoglicemiantes/administração & dosagem , Índia , Insulina/administração & dosagem , Masculino , Análise de Regressão
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