[Combined effect of musically-modulated electrical current and mineral drinking water from Khadyzhensky spring in experimental atherosclerosis]. / Sochetannoe deistvie muzykal'no-modulirovannogo élektricheskogo toka i pit'evoi vody Khadyzhenskogo mestorozhdeniia pri éksperimental'nom ateroskleroze.

Male rats with experimental atherosclerosis drank mineral water (Khadyzhensky spring) and were exposed to music-modulated electric current. This combined treatment showed synergism of physical (current) and balneological (mineral water) factors providing lipolytic, antioxidant, stress-limiting and antiinflammatory intravascular effects and recovery of microcirculatory processes.

[Histogenetic, metabolic, and immunologic aspects of the effect of infrared laser radiation on injured skeletal muscles from irradiated and nonirradiated rats]. / Gistogeneticheskie, metabolicheskie i immunologicheskie aspekty deistviia infrakrasnogo lazernogo izlucheniia na travmirovannuiu obluchennuiu skeletnuiu myshtsu krys.

Using biochemical, histological, morphometric and cytogenetic methods, it was shown that low-intensive infrared laser radiation (total dose 3.6 J/cm2), applied to the injured rat skeletal muscles, stimulated metabolism and regeneration more efficiently in the muscles locally exposed to 20 Gy X-rays compared to the unexposed muscles. The laser irradiation promoted postradiative recovery in bone marrow cells, but did not provide normalization in thymus lymphocyte activity.

[Experimental study of the role of essential trace elements of mineral waters in prevention of atherosclerosis risk factors]. / Uchastie éssentsial'nykh mikroélementov mineral'nykh vod v ustranenii faktorov riska ateroskleroza v éksperimente.

Hormonal and lipid spectra of the blood serum; antioxidant, biosynthetic, microcirculatory and elastic-inhibitory activity in the myocardium and liver; proliferative and genetic activity in the thymus; microcirculation and destruction in rats with atherosclerosis drinking Khadyzhenskaya mineral water and solution of natural macro- and trace elements in the spring water (temarox) in two dilutions. It was found that elimination of atherosclerosis risk factors in rats was most complete in a course temarox drinking in dilution 1/8000.

[The physiological and physicochemical mechanisms of the therapeutic and prophylactic actions of a musically modulated electrical current in experimental atherosclerosis]. / Fiziologicheskie i fiziko-khimicheskie mekhanizmy lechebnogo i profilakticheskogo deistviia muzykal'no-modulirovannogo élektricheskogo toka pri éksperimental'nom ateroskleroze.

In experimental atherosclerosis it is shown that frontomastoid course application of music-modulated electric current prevents oxidant modification of low density lipoproteins in the myocardium, cerebral cortex and liver. This antioxidant effect eliminates one of the principal risk factors of atherosclerosis.

[Recovery processes in the cerebral cortex, myocardium and thymus of rats with experimental atherosclerosis exposed to low-frequency electromagnetic fields on the head]. / Vosstanovitel'nye protsessy v kore golovnogo mozga, miokarde i timuse krys s éksperimental'nym aterosklerozom pri vozdeistviiakh nizkochastotnymi élektromagnitnymi poliami na golovu.

Studies of animals with experimental sclerosis has shown that a course of 10 procedures of alternative magnetic field (AMF) (50 Hz, 30 mT, 3 min daily) promotes partial recovery of the lipid spectrum and corrects vasomotor-metabolic disturbances in the cerebral cortex, myocardium and thymus caused by atherosclerosis. Combination of AMF with constant magnetic field in the same regime and location does not produce a hypolipidemic effect in atherosclerotic animals and this, in combination with increased vascular permeability may aggravate the condition. Activated microcirculation, antioxidant and antiproteinase effects in activation of biosynthetic processes in the cerebral cortex reflect inhibition in the CNS in this combined effect and create conditions for a hypotensive effect.

[Activity of the genome of cardiomyocytes as an indicator of the development of adaptive changes in the myocardium following exposure of the central nervous system to electromagnetic fields]. / Aktivnost' genoma kardiomiotsitov kak pokazatel' razvitiia adaptivnykh izmenenii v miokarde pri vliianii élektromagnitnykh polei na tsentral'nuiu nervnuiu sistemu.

Methods of cardiomyocyte nuclei isolation from the myocard homogeneous mixture, and of cardiomyocyte genome activity estimation were elaborated. In the experiments with hyperlipoproteidemic rats, cardiomyocyte genome activity was shown to reflect the primary adaptive changes in the myocard, and to serve a reliable index of their influence on the CNS regulatory centres exposed to electromagnetic field, which is used for hyperlipoproteidemia treatment. The cardiomyocyte genome activity was used to distinguish between three types of development of adaptive reactions in the myocard.

[Experimental study of the effect of pulsed infrared laser radiation on skeletal muscle regeneration after mechanical trauma]. / Eksperimental'noe izuchenie vliianiia impul'snogo infrakrasnogo lazernogo izlucheniia na regeneratsiiu skeletnoi myshtsy posle mekhanicheskoi travmy.

Impulse infrared laser radiation (0.89 microm) was examined for effect on regeneration of cross-cut musculus gastrocnemius in adult rats (ten 3-min exposures, 2-3 procedures weekly for one month after the operation, modulating frequency 10 Hz, total course dose 3.6 J/cm2). Histological, morphometric and biochemical parameters of muscular regenerates as well as biochemical serum indices show enhanced regeneration of the skeletal muscle. Formation of the muscular organ ends earlier vs untreated muscles. This was accompanied with more active sclerotization of the muscular regenerate.

[Effect of infrared radiation and combination of it with constant and alternating magnetic fields on the recuperative processes in the thymus, liver, and blood of stressed rats]. / Vliianie infrakrasnogo izlucheniia i ego sochetaniia s postoiannymi i peremennymi magnitnymi poliami na vosstanovitel'nye protsessy v timuse, pecheni i krovi stressirovannykh krys.

Changes in thymic cells activity in stressed animals were compared to the level of 11-oxycorticosteroids in the blood and antioxidant hepatic activity in exposure of the hepatic projection region and solar plexus to varying doses of infrared radiation and its combination with constant or alternating magnetic fields. It was shown that combined action of constant or variable (pulsed with negative semiperiods) magnetic fields and infrared radiation in the above exposure promotes optimal conditions for regeneration in stressed rats.

[Changes in the proteinase-inhibitor system of rats with hyperlipoproteinemia during transcerebral exposures to a 100-Hz-frequency pulse current and to an ultrahigh-frequency field]. / Izmeneniia v sisteme proteinazy--ingibitory u krys s giperlipoproteidemiei pri transtserebral'nykh vozdeistviiakh impul'snym tokom s chastotoi 100 Gts i ul'travysokochastotnym polem.

Experiments on 36 male rats with experimental hyperlipoproteinemia demonstrated that transcerebral exposure to impulse current (100 Hz, 2mA) aggravates atherogenic alterations, provokes hyperactivation of kallikrein-kinin system and unbalance of elastase inhibitory activity in the serum and myocardium. The latter may contribute to better vascular permeability for low-density lipoproteins, to development of edema of vascular intima, lability of cellular and lysosomal membranes with hydrolysis of elastine and collagen fibers of myocardial vessels and other organs. Transcerebral exposure to electromagnetic UHF field (40.68 MHz) is not hypolipidemic but has no negative effect on experimental atherosclerosis, promotes normalization of kallikrein-kinin system in the serum, activation of this system in the myocardium and cerebral cortex, correction of destructive processes in the serum and cerebral cortex with a risk of their development in the myocardium.

[The biological action of a musically modulated electric current]. / Biologicheskoe deistvie muzykal'no-modulirovannogo élektricheskogo toka.

The authors suggest to use music-modulated electric current as an adequate physiologic stimulator and stress-limiting factor as it appeared to enhance functional ability of the central nervous system and activate biosynthesis in the tissues supporting active adaptive reactions.

[The combined action of infrared radiation and permanent and alternating magnetic fields in experimental atherosclerosis]. / Kombinirovannoe deistvie infrakrasnogo izlucheniia, postoiannogo i peremennogo magnitnykh polei pri éksperimental'nom ateroskleroze.

Paravertebral exposure to infrared radiation (0.87 micron, 5 mW) and permanent magnetic field in combination with one- and two-semiperiodic alternative magnetic fields (50 Hz, 15-30 mT) was studied in respect to the action on adaptive reactions in animals with experimental atherosclerosis. Complex consisting of infrared radiation, permanent magnetic field and one-semiperiodic pulse alternative magnetic field was most effective in restoration of vasomotor-metabolic and immune disturbances accompanying development of atherosclerosis.

[A comparative analysis of the action of red and infrared laser radiation and ultrasound on the regeneration of locally irradiated skeletal muscle and on immune system function in the rat]. / Sravnitel'nyi analiz deistviia krasnogo, infrakrasnogo lazernogo izlucheniia i ul'trazvuka na regeneratsiiu lokal'no obluchennoi skeletnoi myshtsy i sostoianie immunnoi sistemy krysy.

The study was made of a regeneration ability of the rat skeletal muscle which had been mechanically injured and exposed to a 20 Gy irradiation, of the thymus and bone marrow condition after local exposure of the muscle to red and infrared laser radiation and ultrasound. These factors were found to stimulate regeneration of the injured soft tissues and to reduce cytogenetic damage to bone marrow cells in the irradiated zone under growing immunosuppression. The stimulation was most potent in prolonged exposure to the ultrasound.

[The development of adaptive body reactions after intensive physical loading]. / Razvitie adaptivnykh reaktsii organizma posle intensivnoi fizicheskoi nagruzki.

30 min and 3 hours after intensive exercise (swimming) rats developed both microcirculatory compensatory-adaptive changes in the myocardium, cerebral cortex, liver and destruction at the level of membrane connective tissue structures especially manifest in the myocardium early after the exercise.

[The possibilities for regulating thymus cell activity with the transcerebral use of physical factors]. / Vozmozhnosti reguliatsii aktivnosti kletok timusa pri transtserebral'nom primenenii fizicheskikh faktorov.

The authors discuss experimental findings on physical factors (impulse currents of different frequencies, SHF and IR laser radiation, coherent and non-coherent red light) effect on thymic cell genome in transcerebral exposure in models of some diseases running with immune disorders.