Assuntos
Púrpura , Vasculite , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Hematúria , Humanos , Vasculite por IgA , Imunoglobulina A , Masculino , Pessoa de Meia-Idade , Púrpura/complicações , Púrpura/diagnóstico , Púrpura/fisiopatologia , Estudos Retrospectivos , Vasculite/complicações , Vasculite/diagnóstico , Vasculite/fisiopatologia , Adulto JovemRESUMO
Dermatomyositis (DM) is an idiopathic inflammatory myopathy characterized by proximal muscle weakness associated with a distinct cutaneous eruption. The association of DM with malignancy has been extensively described in the literature. Patients with DM that also have transcriptional intermediary factor 1γ (TIF1γ) autoantibodies (anti-p155, anti-p155/140) have higher rates of malignancy when compared to those without the autoantibody. We report the case of a 65-year-old woman with TIF1γautoantibody positive dermatomyositis associated with a non-functional pancreatic neuroendocrine tumor (PNET). Surgical resection of the PNET resulted in significant clinical improvement and a reduction of TIF1γ autoantibody levels in our patient.
