Cuidados de Enfermería en el tratamiento con hipotermia en la encefalopatía hipóxico-isquémica del recién nacido / Nursing care in hypothermia treatment for newborns with hypoxic-ischemic encephalopathy

Objetivo: analizar la evidencia científica disponible sobre el tratamiento con hipotermia y los cuidados de Enfermería en la encefalopatía hipóxico-isquémica del recién nacido. Método: revisión narrativa de la literatura. Se realizó una búsqueda bibliográfica en diferentes bases de datos, plataformas, bibliotecas y repositorios, que incluían entre otras PubMed, Cochrane, Lilacs, Enfispo, Cuiden, Scielo, etc. Se usaron los términos combinados "hipoxia- isquemia encefálica", "hipotermia inducida", "recién nacido" y "atención de Enfermería". La búsqueda se limitó a artículos científicos de neonatología y pediatría, publicados entre 2006 y 2017, en castellano o inglés. Resultados: se identificaron 29 estudios que hacían referencia al tratamiento con hipotermia en la encefalopatía hipóxico-isquémica (EHI) del recién nacido, así como de los cuidados de Enfermería. Diversos estudios han demostrado que la hipotermia aplicada antes de las seis horas de vida y mantenida durante 72 horas, reduce la mortalidad y lesiones cerebrales. Existe controversia en su aplicación en la encefalopatía hipóxico-isquémica severa o moderada, pero en las dos se obtienen resultados favorables. No hay ninguna terapia que combinada con la hipotermia mejore su eficacia. El éxito de este tratamiento requiere del esfuerzo de un equipo multidisciplinar. La profesión enfermera tiene un papel fundamental en su aplicación y ha de incluir también la atención a los padres durante todo el proceso. Conclusiones: la evidencia disponible apoya que la hipotermia inducida reduce la mortalidad y las secuelas neurológicas en recién nacidos afectados. Queda pendiente un mayor control a lo largo de los años de estos neonatos. Son necesarias otras estrategias que combinadas con la hipotermia inducida reduzcan el impacto de la encefalopatía hipóxico-isquémica

Objective: to analyze the scientific evidence available about hypothermia treatment and Nursing care for newborns with hypoxic-ischemic encephalopathy. Method: a narrative review of literature. A bibliographic search was conducted in different databases, platforms, libraries and repositories, including PubMed, Cochrane, Lilacs, Enfispo, Cuiden, Scielo, etc. The following combined terms were used: "hipoxia- isquemia encefálica" (hypoxic-ischemic encephalopathy), "hipotermia inducida" (induced hypothermia), "recién nacido" (newborn) and "atención de Enfermería" (Nursing care). The search was limited to scientific articles on Neonatology and Paediatrics published between 2006 and 2017, in Spanish and English. Results: twenty-nine (29) studies were identified regarding hypothermia treatment for newborns with hypoxic-ischemic encephalopathy (HIE) as well as Nursing care. Different studies have demonstrated that applying hypothermia before the first 6 hours of life, and maintaining it for 72 hours, will reduce mortality and brain damage. There is some controversy regarding its application in severe or moderate hypoxic-ischemic encephalopathy, but favourable results are obtained in both. No therapy will improve the efficacy of hypothermia when used in combination. The success of this treatment requires the effort of a multidisciplinary team. Nurses as professionals will play an essential role in its application, with must also include care for parents during the entire process. Conclusions: the evidence available supports that induced hypothermia will reduce mortality and neurological consequences in newborns. Further follow-up over the years should be conducted in these newborns. Other strategies are required, to be used in combination with induced hypothermia, for a reduction in the impact of hypoxic-ischemic encephalopathy

The effectiveness of a school-based substance abuse prevention program: 18-month follow-up of the EU-Dap cluster randomized controlled trial.

AIM: To evaluate the effectiveness of a school-based substance abuse prevention program developed in the EU-Dap study (EUropean Drug Addiction Prevention trial). MATERIALS AND METHODS: Cluster Randomized Controlled Trial. Seven European countries participated in the study; 170 schools (7079 pupils 12-14 years of age) were randomly assigned to one of three experimental conditions or to a control condition during the school year 2004/2005. The program consisted of a 12-h curriculum based on a comprehensive social influence approach. A pre-test survey assessing past and current substance use was conducted before the implementation of the program, while a post-test survey was carried out about 18 months after the pre-test. The association between program condition and change in substance use at post-test was expressed as adjusted prevalence odds ratio (POR), estimated by multilevel regression models. RESULTS: Persisting beneficial program effects were found for episodes of drunkenness (any, POR=0.80; 0.67-0.97; frequent, POR=0.62; 0.47-0.81) and for frequent cannabis use in the past 30 days (POR=0.74; 0.53-1.00), whereas daily cigarette smoking was not affected by the program as it was at the short-term follow-up. Baseline non-smokers that participated in the program progressed in tobacco consumption to a lower extent than those in the control condition, but no difference was detected in the proportion of quitters or reducers among baseline daily smokers. CONCLUSION: The experimental evaluation of an innovative school curriculum based on a comprehensive social influence approach, indicated persistent positive effects over 18 months for alcohol abuse and for cannabis use, but not for cigarette smoking.