[Emergency therapy measures in drug-induced anaphylactic shock]. / Mery neotlozhnoi terapii anafilakticheskogo shoka, vyzvannogo lekarstvami.

The authors analyze 10 cases with anaphylactic shock developing after administration of various drugs. The rate of the allergic reaction development depends on the degree of the body sensitization and on the route of the drug administration.

[Effect of tamponade on the nucleotide composition and cytosine methylation level of DNA in the heart muscle of dogs]. / Vliianie tamponady na nukleotidnyi sostav i uroven' metilirovaniia tsitozina DNK v myshtse serdtsa sobak.

Base composition and quantitative changes in the 5-methylcytosine (m5c) content in DNA isolated from male dogs' heart muscle under the acute tamponade have been studied. Due to the effect of tamponade statistically reliable decrease (15%) in m5c content in DNA has been found to take place in experiment in comparison with control. Possible mechanisms of DNA methylation decrease by cytosine are under discussion.

[Early morphologic changes in the myocardium after a wound of the heart complicated by hemopericardium (experimental study)]. / Rannie morfologicheskie izmeneniia miokarda posle raneniia serdtsa, oslozhnennogo gemoperikardom (éksperimental'noe issledovanie).

The myocardia of 20 dogs with penetrating injuries of the right ventricles were studied morphologically and histochemically. Microcirculatory disorders found in the myocardium included overfilled venous and capillary bed that eventually led to capillary stasis, interstitial edema, hemorrhagic foci, arteriolosclerosis. For the first time focal disseminated injuries of cardiomyocytes of a segmental, zonal, and contractural type were detected. In line with these lesions, earlier cardiomyocytic changes were found, such as margination of nuclear chromatin, clarification of karyoplasm, interfibrillar edema of sarcoplasm with subsequent loosening and aggregation of myofibrils. This complex of morphologic changes was invariably found in the myocardia of both ventricles in the dogs dead 10-90 minutes after cardiac injury.