[Clinical and experimental investigation on the radioprotective effect of riboxine in low-dose fractionated irradiation]. / Kliniko-éksperimentalnoe issledovanie radiozashchitnoi éffectivnosti riboksina pri fraktsionirovannom obluchenii v malykh dozakh.

In experiments with dogs (fractionated y-irradiation, accumulated dose 1Gy) as well as in clinical testing of the group of men, recieved 0,25 Gy being engaged in the Chernobyl NPS disaster repairment, the positive influence of riboxin (purine nucleoside) course treatment on parameters of peripheral blood and non-specific resistance system has bee n shown.

[Effect of riboxine on mice resistance to long-term gamma-irradiation in non-lethal dose]. / Vliianie riboksina na rezistentnost myshei k prolongirovannomu gamma-oblucheniiu v neletalnoi doze.

In experiments with mice subjected to long-term irradiation with a non-lethal dose of 4 Gy, (0.017 Gy/min), it has been shown that the number of chromosome aberrations in myelocaryocytes is reduced, the cell precursors pool in the bone marrow and the germinative epithelium are unchanged, the number of lipid radiotoxins decreases, and cell membranes are stabilized after a single dose of a purine nucleoside, riboxine (150 mg/kg, 12 h prior to irradiation).