RESUMO
Addition of splenocytokine therapy to combined therapy of peptic ulcer accelerated healing and prolonged remission.
Assuntos
Citocinas/uso terapêutico , Imunidade Celular/imunologia , Imunoterapia/métodos , Úlcera Péptica/tratamento farmacológico , Úlcera Péptica/cirurgia , Baço/química , Adulto , Idoso , Animais , Peptídeos Catiônicos Antimicrobianos/metabolismo , Proteínas Sanguíneas/metabolismo , Proteínas do Sistema Complemento/metabolismo , Endoscopia Gastrointestinal , Feminino , Hemofiltração/métodos , Humanos , Linfócitos/imunologia , Masculino , Pessoa de Meia-Idade , Muramidase/metabolismo , Úlcera Péptica/imunologia , Baço/imunologia , Sus scrofa , Extratos de Tecidos/uso terapêuticoRESUMO
Female patient with extensive skin burn (I-II-IIIAB skin burn, total area 40%, area of IIIB degree 30%) was treated using transplantation of allogenic fibroblast-like bone marrow mesenchymal stem cells onto the surface of deep thermal burn. The study of wound healing dynamics after transplantation of allogenic fibroblast-like mesenchymal stem cells confirmed high tempo of wound regeneration in the presence of active neoangiogenesis. Due to this, autodermoplasty of burn wounds could be carried out with good results as early as on day 4 after transplantation of fibroblast-like mesenchymal stem cells; this led to more rapid healing of donor zones and accelerated rehabilitation of the patient.
