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1.
Vestn Otorinolaringol ; 85(4): 70-76, 2020.
Artigo em Russo | MEDLINE | ID: mdl-32885641

RESUMO

The spread of the pandemic of the new coronavirus infection COVID-19 inevitably makes adjustments to the medical care. Given that the main route of transmission is airborne, otorhinolaryngologists are at increased risk of infection. Based on the literature data of leading otorhinolaryngologists, as well as their own experience working with patients with the new coronavirus infection COVID-19, the authors present relevant recommendations on the organization of specialized otorhinolaryngological care in the context of the COVID-19 pandemic. The authors consider the etiology, pathogenesis, and clinical manifestations of COVID-19. The features of the examination of ENT, diagnostic and therapeutic procedures, including the use of silicone hydrotamps to stop the front and rear nose bleeds, developed in L.I. Sverzhevskiy OHRIM, and indications for hospitalization in the ENT hospital. Features of operations on the otorhinolaryngological profile during a COVID pandemic are also described. Summing up, the authors indicate that during the pandemic of the new coronavirus infection COVID-19, otorhinolaryngologists need to adhere to two fundamental principles aimed at preventing the spread of infection: the use of modern effective personal protective equipment and the use of examination methods (surgical treatment methods) that prevent the formation of biological aerosols.


Assuntos
Infecções por Coronavirus , Coronavirus , Pandemias , Pneumonia Viral , Betacoronavirus , COVID-19 , Humanos , SARS-CoV-2
2.
Antibiot Khimioter ; 58(7-8): 17-22, 2013.
Artigo em Russo | MEDLINE | ID: mdl-24757829

RESUMO

The data on the efficacy of cycloferon as an agents of antirelapsing therapy in management of 123 patients with chronic hyperplastic sinusitis are presented. The drug induction of endogenous interferons was validated by the properties of the local mucosal immunity, virus invasion and virus persistence in the nasal an d accessory nasal sinuses mucosa, as well as by different levels ofthe interferon production deficiency. The clinical efficacy was stated in 53% of the cases. The relapses were recorded in 13.1% of the patients treated with cycloferon vs. 33.3% of the patients under the local corticosteroid therapy.


Assuntos
Acridinas/uso terapêutico , Imunidade nas Mucosas/efeitos dos fármacos , Indutores de Interferon/uso terapêutico , Mucosa Nasal/efeitos dos fármacos , Pólipos Nasais/tratamento farmacológico , Sinusite/tratamento farmacológico , Adolescente , Corticosteroides/uso terapêutico , Adulto , Idoso , Doença Crônica , Feminino , Humanos , Interferon-alfa/biossíntese , Interferon-alfa/imunologia , Interferon gama/biossíntese , Interferon gama/imunologia , Masculino , Pessoa de Meia-Idade , Mucosa Nasal/imunologia , Mucosa Nasal/patologia , Pólipos Nasais/imunologia , Pólipos Nasais/patologia , Testes de Função Respiratória , Prevenção Secundária , Sinusite/imunologia , Sinusite/patologia
4.
Vestn Otorinolaringol ; (3): 39-41, 1998.
Artigo em Russo | MEDLINE | ID: mdl-9662978

RESUMO

Local application of hydrogels based on the sorbent regencur with dioxidine was tried for efficacy against chronic purulent maxillary sinusitis in 30 patients versus matched controls. Changes in the subjective and objective manifestations of the disease were registered on the sensor-analog and visual-analog scales. The findings indicate higher efficacy of regencur hydrogels with dioxidine.


Assuntos
Abscesso/tratamento farmacológico , Anti-Infecciosos/farmacocinética , Anti-Infecciosos/uso terapêutico , Maxila/metabolismo , Sinusite Maxilar/tratamento farmacológico , Absorção , Adulto , Idoso , Doença Crônica , Quimioterapia Combinada , Feminino , Géis , Humanos , Masculino , Pessoa de Meia-Idade , Quinoxalinas/uso terapêutico
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