RESUMO
Recently, a new high energy proton microscopy facility PRIOR (Proton Microscope for FAIR Facility for Anti-proton and Ion Research) has been designed, constructed, and successfully commissioned at GSI Helmholtzzentrum für Schwerionenforschung (Darmstadt, Germany). As a result of the experiments with 3.5-4.5 GeV proton beams delivered by the heavy ion synchrotron SIS-18 of GSI, 30 µm spatial and 10 ns temporal resolutions of the proton microscope have been demonstrated. A new pulsed power setup for studying properties of matter under extremes has been developed for the dynamic commissioning of the PRIOR facility. This paper describes the PRIOR setup as well as the results of the first static and dynamic proton radiography experiments performed at GSI.
RESUMO
The content and specific activity of labelled methyl groups of choline and phosphorylcholine in the brain, liver and skeletal muscles of rats was studied as affected by nicotinic acid and prozerin, injected subcutaneously 4h before decapitation. It was found that under the effect of prozerin the specific activity of choline lowers only in the muscles and nicotinic acid evokes its decrease in the liver and muscles. The specific activity of phosphorylcholine lowers in the brain and liver with introduction of prozerin and nicotinic acid. The intensity of phosphorylcholine phosphate renewal increases in the liver and skeletal muscles after introduction of both prozerin and nicotinic acid. The activity of choline dehydrogenase in the liver homogenates lowers only with injection of nicotinic acid.
