RESUMO
Background: Infertility has been a significant problem for couples in recent decades, and the issue can often lie with the male rather than the female. Objective: This study aimed to investigate the effects of fats and minerals intake on semen parameters in infertile men. Materials and Methods: This cross-sectional study was performed on 260 infertile men referred to Isfahan Infertility Clinic, Isfahan, Iran in the summer of 2018. Semen parameters regarding sperm concentration, total motility, normal morphology, and sperm volume were considered. To assess dietary intakes, a validated food frequency questionnaire was used. Results: In the adjusted model, the prevalence of abnormal concentration was 5.23 times higher in the top quartile of calcium intake, compared with the bottom quartile (p = 0.03). Also, the prevalence of abnormal morphology was 68% lower in the third quartile of calcium intake (p = 0.03). Additionally, the prevalence of abnormal concentration was 84% lower in the top quartile of folate intake in comparison to the bottom quartile (p = 0.01) and the prevalence of abnormal morphology was 70% lower in the top quartile of folate intake (p = 0.03). Additionally, the prevalence of abnormal concentration was 72% lower in the top quartile of selenium intake in comparison to the bottom quartile (p = 0.04). Furthermore, in the crude model, the prevalence of abnormal volume was 64% lower in the second quartile of linoleic acid intake rather than the first quartile (p = 0.01). Conclusion: In conclusion, diets containing higher amounts of folate and selenium, and lower amounts of cholesterol, saturated fatty acid and calcium were associated with more favorable semen quality parameters.
RESUMO
BACKGROUND: The present systematic review and meta-analysis were conducted to investigate the effects of ginger on biomarkers of oxidative stress such as glutathione peroxidase (GPx), malondialdehyde (MDA), and total antioxidant capacity (TAC) this meta-analysis was performed. METHODS: Five databases were searched from inception to May 2020 using relevant keywords. Results were reported as bias-corrected standardized mean difference (Hedges' g) with 95 % confidence intervals (CI) using random-effects models. RESULTS: Eleven RCTs were included. Ginger resulted in significantly increased on GPx (Hedges' g: 1.93, 95 % CI: 0.20 to 3.66, P = 0.029) and significant reduction in MDA (Hedges' g: -1.45, 95 % CI: -2.31 to -0.59, P = 0.001), but no significant change in TAC (Hedges' g: 0.42, 95 % CI: -0.03 to 0.88, P = 0.069). Greater reduction in MDA was detected in trials using ≤1 g ginger, lasted <12 weeks, participants aged ≥30 years old, among both gender and were conducted sample size ≤40. TAC was increased by administered high doses of ginger, lasted ≥12 weeks, mean age ≥30, sample size >40, and both gender and female. CONCLUSION: Overall, this meta-analysis demonstrated ginger supplementation decreased MDA and increased GPx but the results showed no significant alterations in TAC activities.
