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Med. intensiva ; 20(2): 52-55, 2003.
Artigo em Espanhol | LILACS | ID: biblio-912434

RESUMO

La injuria pulmonar aguda relacionada con la administración de sangre o sus componentes (TRALI), es producida por una reacción de leucoaglutininas o anticuerpos linfocitotóxicos del plasma dadores contra leucocitos del receptor .Se estima una ocurrencia entre 1.4-2 por 10.000 transfusiones; pero hay consenso que es subreconocido e infrecuentemente referido no obstante ser la segunda causa de muerte vinculada a las reacciones postransfusionales. los síntomas salientes del síndrome incluyen disnea, hipo tensión arterial, fiebre hipoxemia y edema pulmonar. Se presenta entre el inicio de la transfusión y cuatro horas de finalizada , la severidad no tiene relación con el volumen infundido y tiende a resolverse dentro de las 96 horas. Se refiere un paciente que desarrolló TRALI por infusión de plaquetas, con comentarios sobre su patogenia y tratamiento. Palabras claves: TRALI, reacciones a la trasnfusion, distrés respiratorio, concentrado de plaquetas.(AU)


Acute pulmonary injury related to the administration of blood or its components (TRALI), is produced by a reaction of leucoagglutinins or plasma lymphocytotoxic antibodies against leukocytes of the recipient. An occurrence is estimated between 1.4-2 per 10,000 transfusions; but there is a consensus that is sub-recognized and infrequently referred to, despite being the second cause of death linked to post-transfusion reactions. Outgoing symptoms of the syndrome include dyspnea, low blood pressure, fever, hypoxemia, and pulmonary edema. It occurs between the start of the transfusion and four hours after the end, the severity has no relation to the volume infused and tends to resolve within 96 hours. A patient who developed TRALI by platelet infusion is referred to, with comments on its pathogenesis and treatment. Key words: TRALI, reactions to trasnfusion, respiratory distress, platelet concentrate.


Assuntos
Humanos , Síndrome do Desconforto Respiratório do Recém-Nascido , Transfusão de Sangue , Plasma Rico em Plaquetas
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