RESUMO
Clinical, x-ray and morphological characteristics are presented for acute tuberculous pneumonia in 56 patients. The diagnosis was established intravitally in 33, postmortem in 23 of them. The disease started acutely and terminated fulminantly in all the patients. A morphological study stated predominance of exudative-necrotic reaction without phasic and productive changes, the presence of M. tuberculosis in the tissues.
Assuntos
Pneumonia/etiologia , Tuberculose Pulmonar/complicações , Doença Aguda , Adolescente , Adulto , Idoso , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Pulmão/diagnóstico por imagem , Pulmão/patologia , Masculino , Pessoa de Meia-Idade , Necrose , Pneumonia/diagnóstico , Pneumonia/patologia , Radiografia , Tuberculose Pulmonar/diagnóstico , Tuberculose Pulmonar/patologiaAssuntos
Tuberculose Pulmonar/epidemiologia , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Causas de Morte , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Federação Russa/epidemiologia , Fatores Socioeconômicos , Tuberculose Pulmonar/diagnóstico , Tuberculose Pulmonar/mortalidadeRESUMO
The effect of the sodium salts of levorin, isolevorin, nystatin and amphotericin B prepared with the use of sodium desoxycholate and amphoglucamine on the development of fatty degeneration of the liver was studied in rats. Fatty degeneration of the liver was induced in the animals by the diet deficient in choline and administration of alcohol (10 g/kg). Most of the studied antibiotics inhibited the development of the liver fatty degeneration. The only exclusion was amphotericin B prepared with the use of sodium desoxycholate which did not influence the level of the liver fatty degeneration. Sodium levorin (10 mg/kg) produced the most pronounced normalizing effect on the lipid metabolism in the liver. Complication of mycoses with fatty degeneration of the liver should not be considered as a contraindication to their treatment with polyenic antibiotics.