[The location of the infecting tick bite and the severity of the course of tick-borne encephalitis]. / Lokalizatsiia zarazhaiushchego ukusa kleshcha i tiazhest' techeniia kleshchevogo éntsefalita.

Analysis of 846 epidemiological charts of unvaccinated tick-borne encephalitis patients in the period of 1956-1985 established that in 21% cases the disease resulted from multiple bites of the ticks, in 67.3% it occurred from single bites. In 11.7% of the patients, the bite was denied. Single infecting bites were mostly those of the head and neck (39.2% cases), especially frequent among children (84.9%). The upper part of the body and hands were bitten less frequently (16.7 and 12.5%, respectively). Other sites of the bite were reported in 6-10%. The most complicated pattern of tick-borne encephalitis is observed in case of multiple bites: two-fold increase in mortality rates compared to single bites (23.2 vs. 10.7%) and higher percent of focal forms (72.7 vs. 56.5%). In case of the single bites a certain correlation is observed between the site of the bite and the outcome of the disease: fatal outcomes are most frequent in case of the bites in the axilla, arms (14-16%), head and neck (11.2%), and less frequent in case of the bites in the lower limbs (5.9%) and groin (0). The nature of the infecting bite determines, to a great extent, the pathogenesis and outcome of the disease. The prevention of multiple bites would help considerably to reduce mortality rates.

[The spatial-temporal structure of fluctuations in tick-borne encephalitis morbidity in the Maritime Territory]. / Prostranstvenno-vremennaia struktura kolebanii zabolevaemosti kleshchevym éntsefalitom v Primorskom krae.

The annual dynamics of the epidemic process in tick-borne encephalitis and its spread in the Maritime Territory, endemic for this infection, have been studied. The study has shown that in the central mountainous regions grown with boreal forest, in contrast to the rest of this focal area, a higher morbidity level and more severe outcomes of this infection are observed. This indicates that in those regions more ancient nuclei of the endemic area of this infection with the main stable elements of the natural focus are preserved.

[Correlations of the indices of tick-borne encephalitis morbidity in the Maritime Territory with natural factors]. / Korreliativnye sviazi pokazatelei zabolevaemosti kleshchevym éntsefalitom v Primorskom krae s nekotorymi prirodnymi faktorami.

The comparison of the absolute figures of the tick-borne encephalitis morbidity and mortality rates in the Primorye Territory for 16-22 years with the climatic parameters and the characteristics of the natural focus in the key area has allowed one to reveal close relationship between the two above-mentioned epidemiological characteristics and such factors as the intensity of monsoon rains and the size of the population of large-toothed redback voles in the previous year. Multiple regression equations suitable for the prognosis of the morbidity and mortality levels in the territory for the coming year have been set up.