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Curr Drug Targets ; 22(10): 1183-1195, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33475056

RESUMO

Oral route of administration is widely accepted and desired because of its versatility, convenience, and, most importantly, patient compliance. Multiparticulate systems like granules and pellets are more advantageous when compared to single-unit dosage forms, as they are capable of distributing the drug more evenly in the gastrointestinal tract. The current paper focuses on pellets, the merits and demerits associated, various pelletization techniques, and their characterization. It also focuses on how pellets can be employed for drug delivery is controlled and sustained release formulations. It gives a complete emphasis on the drug and excipients that can be used in pellet formation, the marketed formulations, and the research pertaining to pellets.


Assuntos
Composição de Medicamentos , Sistemas de Liberação de Medicamentos , Excipientes , Administração Oral , Preparações de Ação Retardada , Implantes de Medicamento , Humanos , Solubilidade
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