Genotype B of Killer Cell Immunoglobulin-Like Receptor is Related with Gastric Cancer Lesions.

NK cells are important in innate immunity for their capacity to kill infected or cancer cells. The killer cell immunoglobulin-like receptors (KIR) are a family of polymorphic genes with inhibitory and activating functions. The main driving force for gastric cancer (GC) development is a chronic response, which causes an increase of NK cells in the gastric mucosa. The aim of this work was to study polymorphisms in KIR genes in patients with either GC or non-atrophic gastritis (NAG). We studied 242 patients (130 with NAG and 112 with GC) and contrasted with 146 asymptomatic individuals. We analyzed diversity in the content and localization of KIR genes in the different clinical groups studied. Four activating and one inhibitory genes were associated with GC: 2DS1 (OR 3.41), 2DS3 (OR 4.66), 2DS5 (OR 2.25), 3DS1 (OR 3.35) and 2DL5 (OR 3.6). The following were also found as risk factors for GC: Bx genotype (OR 4.2), Bx-Bx centromere-telomere (OR 2.55), cA01|cB03 (OR 36.39) and tB01|tB01 (OR 7.55) gene content and three B motifs (OR 10.9). Polymorphisms in KIR genes were associated with GC and suggest that mutated NK cells may contribute to GC development by increasing gastric mucosa inflammation, leading to constant tissue damage.

Comportamiento de la temática educación médica en revistas científico tecnológicas del portal de la Biblioteca Virtual de Salud / The medical education theme in the journals of the virtual library of health

Se realizó una investigación de tipo descriptivo transversal, con el objetivo de describir el estado del arte en relación al tema de educación médica en las Revistas Médicas Cubanas certificadas por el CITMA, publicadas en el Portal de la Biblioteca Virtual de Salud. Se aplicaron métodos de nivel teórico y los empíricos estuvieron conformados por una revisión documental de las Revistas Médicas Cubanas certificadas por el CITMA, disponibles en el portal de la BVS. Se observa que las revistas auspiciadas por instituciones publican más trabajos de educación médica que aquellas que pertenecen a Sociedades Científicas. Se constató que en general es muy reducido el número de publicaciones en el tema de Educación Médica Superior, con excepción de la Revista de Educación Médica Superior, que es exclusiva para estos temas y cuenta en este momento con un portal académico. Se señaló la necesidad de ampliar el espacio para publicar artículos que aborden temáticas de este tipo(AU)

An investigation of cross descriptive type was carried out, with the objective to describe the state of the art of the Cubans Medical Magazines certificated by the CITMA, published in the Virtual Library of Health (BVS), relating to the theme of medical education. A documentary review of the Cubans Medical Magazines certificated by the CITMA, available in the entry of the BVS, was carried out. It is observed that the magazines promoted by institutions publish more works of medical education than those that belong to Scientific Societies. It was verified that in general is very reduced the number of publications in the theme of Superior Medical Education, with exception of the Magazine of Superior Medical Education, that is exclusive for these themes. It was indicated the need to expand the space to publish articles that undertake subject matter of this type(AU)

Comportamiento de la temática educación médica en revistas científico tecnológicas del portal de la Biblioteca Virtual de Salud / The medical education theme in the journals of the virtual library of health

Se realizó una investigación de tipo descriptivo transversal, con el objetivo de describir el estado del arte en relación al tema de educación médica en las Revistas Médicas Cubanas certificadas por el CITMA, publicadas en el Portal de la Biblioteca Virtual de Salud. Se aplicaron métodos de nivel teórico y los empíricos estuvieron conformados por una revisión documental de las Revistas Médicas Cubanas certificadas por el CITMA, disponibles en el portal de la BVS. Se observa que las revistas auspiciadas por instituciones publican más trabajos de educación médica que aquellas que pertenecen a Sociedades Científicas. Se constató que en general es muy reducido el número de publicaciones en el tema de Educación Médica Superior, con excepción de la Revista de Educación Médica Superior, que es exclusiva para estos temas y cuenta en este momento con un portal académico. Se señaló la necesidad de ampliar el espacio para publicar artículos que aborden temáticas de este tipo(AU)

An investigation of cross descriptive type was carried out, with the objective to describe the state of the art of the Cubans Medical Magazines certificated by the CITMA, published in the Virtual Library of Health (BVS), relating to the theme of medical education. A documentary review of the Cubans Medical Magazines certificated by the CITMA, available in the entry of the BVS, was carried out. It is observed that the magazines promoted by institutions publish more works of medical education than those that belong to Scientific Societies. It was verified that in general is very reduced the number of publications in the theme of Superior Medical Education, with exception of the Magazine of Superior Medical Education, that is exclusive for these themes. It was indicated the need to expand the space to publish articles that undertake subject matter of this type(AU)

[Gender perspective in health care teaching: a pending task]. / Perspectiva de género en la formación de profesionales de la salud: Una tarea pendiente.

BACKGROUND: Gender must be considered in the design and implementation of health policies to safeguard equity and accomplish sanitary objectives. AIM: To identify gender perspective in the curricula of five health care careers in the Universidad Austral de Chile. To identify the situation of women in the teaching profile of such curricula. MATERIAL AND METHODS: An exploratory and descriptive study with a critical reading of the structure of the programs of 217 courses. Revision of official academic registries. RESULTS: Gender is usually not included in the curricula of health care careers. The generic language conceals female academics and students. There was a scarce inclusion of cross sectional issues such as collaborative work, interpersonal and democratic relationship, equity and critical analysis. There were no differences in academic achievements between female and male students. The contractual profile of female academics reproduces the gender inequity of the work market. CONCLUSIONS: The inclusion of gender is a pending task in the training of health care professionals.

Perspectiva de género en la formación de profesionales de la salud: Una tarea pendiente / Gender perspective in health care teaching: A pending task

Background: Gender must be considered in the design and implementation of health policies to safeguard equity and accomplish sanitary objectives. Aim: To identify gender perspective in the curricula of five health care careers in the Universidad Austral de Chile. To identify the situation of women in the teaching profile of such curricula. Material and methods: An exploratory and descriptive study with a critical reading of the structure of the programs of 217 courses. Revision of official academic registries. Results: Gender is usually not included in the curricula of health care careers. The generic language conceals female academics and students. There was a scarce inclusion of cross sectional issues such as collaborative work, interpersonal and democratic relationship, equity and critical analysis. There were no differences in academic achievements between female and male students. The contractual profile of female academics reproduces the gender inequity ofthe work market. Conclusions: The inclusion of gender is a pending task in the training of health care professionals).

Violencia doméstica y sexualidad / Domestic violence and sexuallity

Background: women's reproductive health is closely related to the conditions in which intercourse is carried out with the sexual partner. Physical and emotional abuse is expressed as loss of bonds, reduction in self esteem and deterioration in interpersonal relationships. Aim: to assess the effects of domestic violence on pregnant women attitudes towards sexual relations with their partners, and to critically analyze the dependence of these variables on biosociodemographic factors, socioeconomic status and family functioning. Material and methods: sixty three pregnant women with a domestic violence background (index group) and 43 women without such background (control group) were subjected to a structured survey including questions about biosociodemographic variables, socioeconomic status, family relations, couple interactions and questions about attitudes towards sexual relations. Results: domestic violence was caused by the woman's partner or ex partner in 73 percent of cases. A greater family dysfunction and disturbance in the couple's relation was observed in the index group (p< 0,05). Association tests and multiple correspondence analysis did not show a clear correspondence between variables related to a woman's attitude towards sex relations and the risk of domestic violence. Conclusions: this quantitative methodology was unable to identify the reasons, interpretations and meanings that women with a background of violence, give to features associated with their sexuality

Maternidad en adolescentes: perfil del patrón de crecimiento del niño durante el primer año de vida / Maternity in adolescents: profile of the growth pattern of the children during the first year of life

Objetivos: 1. examinar el perfil del patrón del crecimiento en el primer año de vida de los hijos de madres adolescentes atendidas por el Programa de Atención Integral de la Adolescente Embarazada (P.A.I.A.E.), 2. analizar la influencia de factores maternos y neonatales sobre los parámetros antropométricos en tres momentos del primer año de vida del lactante. Metodología: se diseñó un estudio de seguimiento longitudinal de una cohorte única de 125 lactantes. Variables independientes: peso, talla, perímetro craneano al nacer, sexo, apgar al minuto y cinco minutos, edad gestacional pediátrica, clasificación de peso según edad gestacional y variables biodemográficas maternas. Variables dependientes: peso, talla y su incremento al mes, seis meses y al año de vida de niño. Procedimientos estadísticos convencionales fueron usados en el análisis de los datos. Resultados: el crecimiento antropométrico del lactante muestra que los valores observados de peso y talla presentan mejores resultados en el peso que en la talla, y los promedios alcanzados son más bajos en niñas que en niños. El peso y el sexo del recién nacido explican el 74,3 por ciento de la variabilidad del peso al mes de vida. La talla, peso y edad gestacional pediátrica al nacer explican el 77,7 por ciento de la variabilidad de la talla al mes de vida. A los seis y doce meses estas variables pierden progresivamente su importancia como variables explicatorias. Conclusiones: después del mes de vida habría otros factores que influyen en el crecimiento antropométrico del lactante hijo de madre adolescente, tema que necesita ser abordado en futuras investigaciones