RESUMO
Dietary cholesterol supplementation was used to increase serum cholesterol concentration in diabetic and non-diabetic rats. With the use of numerous dietary formulations, extremely elevated serum cholesterol concentrations and gastrointestinal intolerance were found. We conclude that there are unacceptable side effects with a vast number of exogenous cholesterol supplemented diets which preclude standard and long-term usage.
Assuntos
Colesterol na Dieta/administração & dosagem , Colesterol/sangue , Diabetes Mellitus/sangue , Animais , Colesterol na Dieta/toxicidade , Diarreia/etiologia , Feminino , Masculino , Ratos , Ratos Endogâmicos Lew , Ratos Sprague-DawleyRESUMO
Renal insufficiency is a rare manifestation of Kawasaki disease. We report a 2.5-year-old boy with Kawasaki disease who developed acute renal failure during the acute phase of his illness. A percutaneous renal biopsy revealed acute interstitial nephritis. No etiological agent could be identified and renal recovery occurred with supportive care alone.
Assuntos
Síndrome de Linfonodos Mucocutâneos/complicações , Nefrite Intersticial/complicações , Injúria Renal Aguda/etiologia , Reação de Fase Aguda , Pré-Escolar , Humanos , Masculino , Síndrome de Linfonodos Mucocutâneos/diagnóstico , Nefrite Intersticial/diagnósticoRESUMO
A technique for percutaneous renal biopsy in children is described which combines the use of ultrasound guidance and a disposable automatic biopsy device. Twenty-five biopsies in 22 children were performed using the Bard Monopty biopsy instrument. Adequate tissue was obtained to aid in diagnosis in 24 of 25 cases. Complications inclused 2 small perinephric hematomas. We conclude that the Bard Monopty biopsy device in association with ultrasonography provides for a safe and reliable technique to perform percutaneous renal biopsy in children.
