Relación entre blefaritis y componentes del síndrome metabólico / Relationship between blepharitis and components of the metabolic síndrome

OBJETIVO: Determinar la relación entre los componentes del síndrome metabólico con la presencia de blefaritis. MÉTODOS: Se incluyeron 60 pacientes con diagnóstico de blefaritis y 30 sujetos control. Se realizaron medidas antropométricas, presión sanguínea y se obtuvieron muestras de sangre venosa periférica en condiciones de ayuno para la determinación de concentración de glucosa, colesterol y triglicéridos. El colesterol de las lipoproteínas de alta densidad (c-HDL) se determinó después de precipitar las lipoproteínas que contienen apoB-100 con ácido fosfotúngstico/Mg2+. La concentración de las lipoproteínas de baja densidad (c-LDL) se calculó utilizando la fórmula de Friedewald modificada por DeLong. RESULTADOS: En el análisis comparativo se encontraron diferencias estadísticamente significativas en la circunferencia de cintura (p = 0,0491), presión arterial sistólica (p = 0,0149), glucosa (p = 0,0045), colesterol total (p = 0,0001), c-HDL (p = 0,0049), c-LDL (p = 0,0266) y triglicéridos (p = 0,0059); mientras que en el IMC y en la presión diastólica no hubo diferencia significativa. CONCLUSIONES: Los resultados encontrados apoyan la hipótesis de que el síndrome metabólico podría ser considerado un factor de riesgo para el desarrollo de blefaritis y su detección oportuna es fundamental para evitar las complicaciones futuras

OBJECTIVE: To determine the relationship between the components of the metabolic syndrome with the presence of blepharitis. METHODS: The study included 60 patients with a diagnosis of blepharitis and 30 control subjects. Anthropometric measurements and blood pressure were recorded, and peripheral venous blood samples were obtained under fasting conditions to determine the concentration of Glucose, Cholesterol, and Triglycerides. High-density lipoprotein cholesterol (HDL-C) was determined after precipitating lipoproteins containing apoB-100 with phosphotungstic acid/Mg2+. The concentration of low density lipoprotein cholesterol (LDL-C) was calculated using the Friedewald formula modified by DeLong. RESULTS: In the comparative analysis, statistically significant differences were found in the waist circumference (P = .0491), systolic blood pressure (P = .0149), glucose (P = .0045), total cholesterol (P = .0001), HDL-C (P = .0049), LDL-C (P = .0266), and triglycerides (P = .0059); while there was no significant differences in the BMI or the diastolic pressure. CONCLUSIONS: The results support the hypothesis that the metabolic syndrome could be considered a risk factor for the development of blepharitis, and its timely detection is essential to avoid future complications

Relationship between blepharitis and components of the metabolic syndrome. / Relación entre blefaritis y componentes del síndrome metabólico.

OBJECTIVE: To determine the relationship between the components of the metabolic syndrome with the presence of blepharitis. METHODS: The study included 60 patients with a diagnosis of blepharitis and 30 control subjects. Anthropometric measurements and blood pressure were recorded, and peripheral venous blood samples were obtained under fasting conditions to determine the concentration of Glucose, Cholesterol, and Triglycerides. High-density lipoprotein cholesterol (HDL-C) was determined after precipitating lipoproteins containing apoB-100 with phosphotungstic acid/Mg2+. The concentration of low density lipoprotein cholesterol (LDL-C) was calculated using the Friedewald formula modified by DeLong. RESULTS: In the comparative analysis, statistically significant differences were found in the waist circumference (P=.0491), systolic blood pressure (P=.0149), glucose (P=.0045), total cholesterol (P=.0001), HDL-C (P=.0049), LDL-C (P=.0266), and triglycerides (P=.0059); while there was no significant differences in the BMI or the diastolic pressure. CONCLUSIONS: The results support the hypothesis that the metabolic syndrome could be considered a risk factor for the development of blepharitis, and its timely detection is essential to avoid future complications.