RESUMO
Cases of red fingers syndrome and nodular vasculitis in patients with hepatitis C have rarely been described. Both red fingers syndrome and nodular vasculitis are characterized by microscopic vasculitis, and it has been hypothesized that hepatitis C plays a role in the pathogenesis of cutaneous disorders such as vasculitis, especially in cryoglobulinaemic vasculitis. We describe the case of a 75-year-old woman diagnosed with chronic hepatitis C who presented with nodular lesions on her right thigh and red fingers syndrome. A skin biopsy taken from a nodule showed infiltration of the vessel walls by mononuclear cells and septal and lobular panniculitis. The diagnosis of nodular vasculitis was established. In our opinion, red fingers syndrome and nodular vasculitis might be related to a vascular reaction of immune-mediated mechanisms induced by hepatitis C.
Assuntos
Eritema/patologia , Hepatite C Crônica/diagnóstico , Paniculite Nodular não Supurativa/patologia , Idoso , Biópsia por Agulha , Diagnóstico Diferencial , Eritema/complicações , Eritema/diagnóstico , Eritema/terapia , Feminino , Seguimentos , Hepatite C Crônica/complicações , Hepatite C Crônica/tratamento farmacológico , Humanos , Imuno-Histoquímica , Paniculite Nodular não Supurativa/complicações , Paniculite Nodular não Supurativa/diagnóstico , Recidiva , Medição de Risco , Índice de Gravidade de Doença , Síndrome , Dedos do PéRESUMO
Two cases of necrotic myelopathy are presented. This is a very rare paraneoplasic syndrome. One patient had clear cell renal carcinoma and other had lymphatic metastasis of malignant melanoma without filiation of the primary tumor. The complete spinal study (MNR, CT, myelography) proved normal. Diagnosis is possible when all other causes of spinal disease have been discarded. Nowadays, it is possible to diagnose this disease premortem. The international literature reviewed showed 31 cases published since 1903, associated mainly to malignant diseases such as lymphomas, lung cancer, renal carcinoma, breast cancer, leukemias, etc. The differential diagnosis appears in the comments, as well as the presentation and evolution of the cases described up until now.
Assuntos
Adenocarcinoma/patologia , Carcinoma de Células Renais/patologia , Neoplasias Renais/patologia , Melanoma/patologia , Mielite/patologia , Neoplasias Primárias Desconhecidas/patologia , Síndromes Paraneoplásicas/patologia , Adulto , Humanos , Metástase Linfática , Masculino , Pessoa de Meia-Idade , Necrose/patologiaRESUMO
The myoblastoma or Abrikossoff' tumor is a kind of harmless tumor that concerns to adult people and whose origin remains being a controversy. We report a new case of Abrikossoff' tumor with a unusual localization and emphasizing on its histogenesis.