RESUMO
Gran versus Host Disease (GVHD) is a common complication in allogenic bone marrow transplants and in some cases, it involves the oral mucosa. Therefore, the appropriate diagnosis and timely treatment is essential to prevent ¡ocal complications which interfere with normal oral functions and facilitate infection spread. We report a 17 years old woman with GVHD associated to ¡ichenoid and ulcerative ¡essions in the oral mucosa, which responded to the topical administration of a 0.1 percent tacrolimus ointment.
Assuntos
Adolescente , Feminino , Humanos , Transplante de Medula Óssea/efeitos adversos , Doença Enxerto-Hospedeiro/etiologia , Doenças da Boca/etiologia , Anemia Aplástica/cirurgia , Doença Enxerto-Hospedeiro/tratamento farmacológico , Imunossupressores/uso terapêutico , Doenças da Boca/tratamento farmacológico , Mucosa Bucal , Tacrolimo/uso terapêuticoRESUMO
Gran versus Host Disease (GVHD) is a common complication in allogenic bone marrow transplants and in some cases, it involves the oral mucosa. Therefore, the appropriate diagnosis and timely treatment is essential to prevent local complications which interfere with normal oral functions and facilitate infection spread. We report a 17 years old woman with GVHD associated to lichenoid and ulcerative lesion in the oral mucosa, which responded to the topical administration of a 0.1% tacrolimus ointment.