[Basophil "degranulation" as an index of the body stress state]. / Degranuliutsiia Bazofilov kak pokazatel' sostoianiia napriazheniia organizma.

A regular "degranulation" development of basophilic leucocytes in the blood has been established not only in cases of the joint and skin allergic reactions but in acute and chronic experimental hemorrhage, skin burns and acute radiation disease. Basophilic "degranulation" denotes the stress state of the organism as a result of stress situations.

[Evaluation of the changes of natural resistance in patients with diffuse peritonitis]. / Otsenka izmenenii estestvennoi rezistentnosti u bol'nykh razlitym peritonitim

A suppression of humoral and cell mechanisms of natural nonspecific resistance was found in patients with diffuse peritonitis. A considerable degranulation of basophilic leucocytes was indicated by the direct Shelley reaction, that evidences alterations in the functional state of these cells. Postoperatively, there is a break in restoration of the activity of properdine and its cofactors, and a considerable suppression of the phagocytic capacity of microphages is noted, that leads inevitably to a reduction of immune reactivity.

[The functional activity of microphages and cation protein in experimental allergic arthritis]. / Funktsional'naia aktivnost' mikrofagov i kationnyi belok pri éksperimental'nom allergicheskom artrite

A reduction of the content of cation protein in microphages was revealed in experimental allergic arthritis with the aid of the fluorescent-microscopic method of cation protein detection and objective recording of its content. Phagocytic activity of these cells diminished in parallel with reduction of the cation protein content. Protective properties of microphages were possibly reduced as a result of allergic alteration of cells leading to their structural and functional reconstruction.