RESUMO
In the United Kingdom, measurements have been made of the concentration of 90Sr in human bone from 1955 to 1970, and in human diet since 1958. A correlation of these two series of observations has enabled estimates to be made of (i) the fraction of the dietary intake of 90Sr that reaches the skeleton, (ii) the rate of turnover of 90Sr in the skeleton, and (iii) the way in which both these parameters vary with age. The results may be used to predict future levels of 90Sr in human bone from measurements of the radionuclide in diet, and also to calculate the radiation doses received by tissues in bone from intakes of 90Sr and 89Sr.
Assuntos
Osso e Ossos/metabolismo , Radioisótopos de Estrôncio/metabolismo , Adolescente , Adulto , Osso e Ossos/análise , Cálcio/análise , Criança , Pré-Escolar , Dieta , Feminino , Contaminação Radioativa de Alimentos/análise , Humanos , Lactente , Masculino , Matemática , Modelos Biológicos , Radioisótopos de Estrôncio/análise , Reino UnidoRESUMO
Cancer mortality has been studied in 1110 women who worked in the U.K. with paint containing radium from 1939 to 1961. Their body contents of radium were small, but they were also irradiated externally by gamma-rays to receive absorbed dose rates of 1-4 mGy per week. Those in the group who were under 30 years of age when they started work show a significantly increased risk of dying from breast cancer. If the excess were due solely to their radiation exposure, it would represent a risk of 20-500 deaths from breast cancer per 10(4) women exposed to 1 Gy, which is consistent with the value used by the International Commission on Radiological Pretection.
Assuntos
Neoplasias da Mama/etiologia , Neoplasias Induzidas por Radiação/etiologia , Doenças Profissionais/etiologia , Doses de Radiação , Neoplasias da Mama/mortalidade , Feminino , Humanos , Concentração Máxima Permitida , Pintura/efeitos adversos , Radiação Ionizante , Fatores de TempoAssuntos
Leucemia Mieloide Aguda/epidemiologia , Leucemia Mieloide/epidemiologia , Leucemia Induzida por Radiação/epidemiologia , Animais , Inglaterra , Peixes/efeitos da radiação , Contaminação Radioativa de Alimentos , Humanos , Resíduos Radioativos , Poluentes Radioativos da Água/efeitos adversosAssuntos
Ovário/metabolismo , Plutônio/metabolismo , Animais , Feminino , Camundongos , Camundongos Endogâmicos CBAAssuntos
Anormalidades Congênitas/epidemiologia , Doenças Genéticas Inatas/epidemiologia , Aborto Espontâneo/genética , Adulto , Idoso , Criança , Pré-Escolar , Aberrações Cromossômicas , Anormalidades Congênitas/genética , Doença das Coronárias/epidemiologia , Doença das Coronárias/genética , Feminino , Morte Fetal/genética , Humanos , Recém-Nascido , Masculino , Pessoa de Meia-Idade , Mutação/efeitos da radiação , Neoplasias/epidemiologia , Neoplasias/genética , Gravidez , Transtornos Psicóticos/genéticaRESUMO
Data now available on the risks of radiation-induced fatal cancer and hereditary disease and radionuclide metabolism suggest that limits on the rates of intake of 90Sr, 226Ra and 239Pu at work, presently recommended by the International Commission on Radiological Protection, might be in need of considerable revision one with another and with the limit for uniform exposure of the whole body.
