1.
Prog Neuropsychopharmacol Biol Psychiatry
; 26(5): 891-5, 2002 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12369262
RESUMO
Adult male rats were administered intrapleural (ipl) or intraperitoneal (i.p.) injection of lipopolysaccharide (LPS), 24 h after being submitted to forced swim test (FST). Four hours after LPS challenge, an increase in pleural and peritoneal leukocyte and neutrophil counts in animals not exposed to FST was noted. FST induced a marked increase in pleural, but not in peritoneal, neutrophil leukocytosis. The results suggest that lowered mood may increase inflammatory response to LPS.