[Use of the Sevac Immunoskintest kit in children]. / Pouzití soupravy Imunoskintest Sevac u detí.

The Immunoskintest SEVAC is a kit of antigens for skin tests to evaluate the state of cellular immunity. By means of this kit 591 children from birth to 15 years were examined: the children suffered from acute diseases of the CNS, respiratory diseases incl. relapsing ones, a malignant tumour, haematological disease, and there were children who were Mantoux II negative and healthy children from children's homes. The value of the index of the skin test was referred to the child's age and sex; the lowest values were recorded in children with immunosuppressive therapy and the highest values of the skin test were found in healthy children and those with acute disease; boys had higher values than girls. In none of the children undesirable side-reaction were recorded after administration of the antigens.

Failure to detect mouse species-specific antigens in Toxoplasmin Sevac.

Toxoplasmin--a highly purified extract from the protozoa Toxoplasma gondii propagated in mice--was tested for the presence of the mouse species-specific antigens by immunodiffusion in agar gel and by PCA test. Neither test gave positive reaction. It was concluded therefore that Toxoplasmin Sevac used for the detection of dermal hypersensitivity to toxoplasma antigens in humans does not contain any detectable contamination by mouse species-specific antigens within the limits of sensitivity of both methods used.