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1.
J Pediatr Orthop B ; 28(3): 235-241, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-30839360

RESUMO

The aim of this study was to evaluate the clinical and radiological results of a double arthrodesis technique for the treatment of equino-plano-valgus foot deformity in pediatric patients affected by cerebral palsy. A retrospective evaluation was performed on 175 feet surgically treated with a talonavicular and calcaneocuboid joint fusion technique. The average age at surgery was 14.7 years (range: 12-20 years). Visual analogue scale for pain score, Gross Motor Function Classification System scale, talonavicular angle, Costa-Bertani angle, and Kite's angle on standard weight bearing radiographs were evaluated preoperatively and postoperatively. The mean clinical follow-up was 62.4 months (range: 12-112 months). The mid Gross Motor Function Classification System scale value did not show a significant improvement in any of the subgroups considered. A significant improvement in the visual analogue scale for pain score value was evident 6 months after surgery. Radiological examination showed a statistically significant improvement in the talonavicular angle (average 7.4°) and the Costa-Bertani angle (average 128.5°). Complications occurred in 8.6% of cases. The described surgical technique is safe and efficacious, and could represent a useful option of treatment of equino-plano-valgus severe deformity in cerebral palsy patients older than 12 years of age.


Assuntos
Artrodese/métodos , Paralisia Cerebral/diagnóstico por imagem , Paralisia Cerebral/cirurgia , Deformidades do Pé/diagnóstico por imagem , Deformidades do Pé/cirurgia , Índice de Gravidade de Doença , Adolescente , Paralisia Cerebral/epidemiologia , Criança , Pé Equino/diagnóstico por imagem , Pé Equino/epidemiologia , Pé Equino/cirurgia , Feminino , Seguimentos , Deformidades do Pé/epidemiologia , Humanos , Masculino , Estudos Retrospectivos , Fatores de Tempo , Resultado do Tratamento , Adulto Jovem
2.
J Reconstr Microsurg ; 34(6): 389-398, 2018 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-29510417

RESUMO

BACKGROUND: We describe the development of a new surgical procedure to be used in the treatment of disruptive brachial plexus (BP) lesions. It is centered on an artificial device designed to assist nerve regeneration by providing a confined and protected environment. Nerve fibers can repair inside the device, while the adverse massive scar-tissue formation is limited to the outside of the device. METHODS: Steps in the development of the procedure were (1) definition of the rationale, (2) design of the device, (3) choice of an in vivo translational model, (4)refinement of the surgical procedure, and (5) performance of an in vivo pilot study as a proof of concept. An interdisciplinary team from several laboratories was involved in this work over a period of 6 years. RESULTS: Results showed the absence of significant scar tissue in the regenerate and the presence of myelinated fibers aligned proximodistally between the stumps. This surgical approach can be seen not only as a definitive treatment but also as an early examination and stabilization before some different surgery will be later performed. It may also be used as additional protection for traditional surgery like end-to-end coaptation. CONCLUSIONS: We conclude that the availability of a suitable device-assisted early treatment, even if not to be considered definitive, could help in addressing the BP lesions at an earlier stage and this may improve the final outcome. Our evidence justifies further experimentation on this approach.


Assuntos
Neuropatias do Plexo Braquial/cirurgia , Plexo Braquial/lesões , Bainha de Mielina/patologia , Regeneração Nervosa/fisiologia , Procedimentos Neurocirúrgicos , Animais , Plexo Braquial/cirurgia , Neuropatias do Plexo Braquial/patologia , Cicatriz , Modelos Animais , Projetos Piloto , Estudo de Prova de Conceito , Coelhos , Ratos , Ovinos
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