[Development of an automated microbiological analyzer].

An automated hematological analyzer, prototype of a quick microbiological diagnostics system, was tested positively for the ability to differentiate microbial cells (six test-strains with different morphological and tinctorial properties) by geometry and dye intensity.

[Microvzor-2: a system for automated dry blood smear analysis]. / Mikrovzor-2: kompleks avtomaticheskogo analiza krovi po sukhomu mazku.

Upgraded system Microvzor-2 for investigation of blood morphology in space flight is composed of soft- and hardware for dry smear image analysis. Ground-based testing showed that it could be utilized to investigate a broad spectrum of blood parameters in space flight, including erythrocytes, hemoglobin content in erythrocytes, volumetric erythrocyte distribution, diagnostics of anisocytosis, and poikilocytosis, leukocytes and leukocyte count. Analyzed are smears prepared from a fixed volume of finger blood. The process consists of smear scanning, input of the vision field images in the spacecraft computer and ensuing automated identification and counting. Information is stored in a dedicated database. Results of analysis are displayed as forms and cell galleries.

[Automated cytophotomorphometric tests of blood smears in general clinical studies and population screening]. / Avtomatizirovannye tsitofotomorfometricheskie testy mazkov krovi dlia obshchei kliniki i skriningovykh obsledovanii naseleniia.

Automation of routine operations of photomorphometry of blood smears realized in the MEKOS-C cytoanalyzer helped create a new level of using a set of cytological tests, such as assessment of the leukocyte and erythrocyte formulae and of the histogram of hemoglobin distribution in red cells, estimation of leukocyte subtypes, assessment of the characteristics of the nucleolar system and the nucleoli-forming sites. Automated complex analysis of an increase in the measured characteristics of red and white blood cells impossible in common microscopy and flow cytoanalyzers appreciably improves the sensitivity and accuracy of tests and extends the range of their application. Low cost of analysis of a blood smear permits the use of MEKOS-C not only in clinical studies, but even in overall prophylactic screenings of the population.