Glyceridic esters of p-methoxycinnamic acid. A new sunscreen of the cinnamate class.

The aim of this work was to investigate whether a 1,3-diacylglycerol moiety can act as enhancer of the photoprotecting action of a new sunscreen of the cinnamate class, owing to its affinity with skin constituents and lower susceptibility to hydrolysis at C-2. The sun protection factors (SPF) for 1,2,3-propanetriol 1,3-dipalmitate-2-p-methoxycinnamate and 1,2,3-propanetriol 1,3-dioctanoate-2-p-methoxy-cinnamate (2.0, 4.5 and 7.5%) were determined. The sunscreen preparations presented SPF values between 4.7 and 16. The results show that although glyceridic esters present higher lipophilicity and are more stable towards enzymatic hydrolysis in vitro, the synthesized triacylglycerols and the standard sunscreen 2-ethylhexyl p-methoxycinnamoyl (EHPM) showed equivalent SPF values for both methods.

Cellulite: a review.

Gynoid lipodystrophy (cellulite) is an extremely controversial topic. A lack of knowledge regarding specific aetiopathogenic factors, as well as the opportunism of some professionals and the media, has fuelled debate regarding the scientific basis of this condition. This article reviews the clinical, epidemiological, histopathological and therapeutic aspects of cellulite.

In vitro and in vivo determinations of sun protection factors of sunscreen lotions with octylmethoxycinnamate.

The aim of this work was to evaluate the correlation between in vitro and in vivo determinations of sun protection factors (SPF) of sunscreen lotions containing the synthetic sunscreen octyl methoxycinnamate. Three sunscreen lotions containing either 2, 4.5 or 7.5% octyl methoxycinnamate were prepared. The in vitro SPFs of these sunscreen lotions were determined according to the spectrophotometric method of Mansur et al. The in vivo SPF values were determined according to the Food and Drug Administration (FDA) method. The results indicate that there was a good correlation between the in vitro and in vivo determinations for the sunscreen lotions examined.

Tumor glomico solitario de localizacao rara. Diagnostico diferencial com sindrome de Parsonage-Turner. / Unusual site of glomus tumor. Differential diagnosis with Parsonage-Turner syndrome

Os autores comentam a incidencia, dificuldades diagnosticas, peculiaridades anatomicas, historico, aspectos clinicos e histopatologicos do tumor glomico solitario.Descrevem um caso de localizacao rara