Polarographic determination of proguanil and chlorhexidine.

The method is based on the cathodic wave obtained for chlorhexidine and proguanil in buffered aqueous dimethylformamide media. Concentrations up to 8 x 10(-5) and 6 x 10(-4)M, respectively, can be determined. The difference in behaviour at various pH values or in the presence of surface-active agents, is useful for characterization of both biguanides.