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1.
Nature ; 586(7827): 47-51, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-32999484

RESUMO

Radiation sensors based on the heating effect of absorbed radiation are typically simple to operate and flexible in terms of input frequency, so they are widely used in gas detection1, security2, terahertz imaging3, astrophysical observations4 and medical applications5. Several important applications are currently emerging from quantum technology and especially from electrical circuits that behave quantum mechanically, that is, circuit quantum electrodynamics6. This field has given rise to single-photon microwave detectors7-9 and a quantum computer that is superior to classical supercomputers for certain tasks10. Thermal sensors hold potential for enhancing such devices because they do not add quantum noise and they are smaller, simpler and consume about six orders of magnitude less power than the frequently used travelling-wave parametric amplifiers11. However, despite great progress in the speed12 and noise levels13 of thermal sensors, no bolometer has previously met the threshold for circuit quantum electrodynamics, which lies at a time constant of a few hundred nanoseconds and a simultaneous energy resolution of the order of 10h gigahertz (where h is the Planck constant). Here we experimentally demonstrate a bolometer that operates at this threshold, with a noise-equivalent power of 30 zeptowatts per square-root hertz, comparable to the lowest value reported so far13, at a thermal time constant two orders of magnitude shorter, at 500 nanoseconds. Both of these values are measured directly on the same device, giving an accurate estimation of 30h gigahertz for the calorimetric energy resolution. These improvements stem from the use of a graphene monolayer with extremely low specific heat14 as the active material. The minimum observed time constant of 200 nanoseconds is well below the dephasing times of roughly 100 microseconds reported for superconducting qubits15 and matches the timescales of currently used readout schemes16,17, thus enabling circuit quantum electrodynamics applications for bolometers.

2.
Sci Rep ; 8(1): 6325, 2018 Apr 20.
Artigo em Inglês | MEDLINE | ID: mdl-29679059

RESUMO

Superconducting microwave circuits show great potential for practical quantum technological applications such as quantum information processing. However, fast and on-demand initialization of the quantum degrees of freedom in these devices remains a challenge. Here, we experimentally implement a tunable heat sink that is potentially suitable for the initialization of superconducting qubits. Our device consists of two coupled resonators. The first resonator has a high quality factor and a fixed frequency whereas the second resonator is designed to have a low quality factor and a tunable resonance frequency. We engineer the low quality factor using an on-chip resistor and the frequency tunability using a superconducting quantum interference device. When the two resonators are in resonance, the photons in the high-quality resonator can be efficiently dissipated. We show that the corresponding loaded quality factor can be tuned from above 105 down to a few thousand at 10 GHz in good quantitative agreement with our theoretical model.

3.
Scand J Med Sci Sports ; 26(8): 885-93, 2016 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-26247789

RESUMO

The aim of this study was to investigate factors that can predict individual adaptation to high-volume or high-intensity endurance training. After the first 8-week preparation period, 37 recreational endurance runners were matched into the high-volume training group (HVT) and high-intensity training group (HIT). During the next 8-week training period, HVT increased their running training volume and HIT increased training intensity. Endurance performance characteristics, heart rate variability (HRV), and serum hormone concentrations were measured before and after the training periods. While HIT improved peak treadmill running speed (RSpeak ) 3.1 ± 2.8% (P < 0.001), no significant changes occurred in HVT (RSpeak : 0.5 ± 1.9%). However, large individual variation was found in the changes of RSpeak in both groups (HVT: -2.8 to 4.1%; HIT: 0-10.2%). A negative relationship was observed between baseline high-frequency power of HRV (HFPnight ) and the individual changes of RSpeak (r = -0.74, P = 0.006) in HVT and a positive relationship (r = 0.63, P = 0.039) in HIT. Individuals with lower HFP showed greater change of RSpeak in HVT, while individuals with higher HFP responded well in HIT. It is concluded that nocturnal HRV can be used to individualize endurance training in recreational runners.


Assuntos
Adaptação Fisiológica , Condicionamento Físico Humano/fisiologia , Resistência Física , Esforço Físico/fisiologia , Corrida/fisiologia , Adulto , Desempenho Atlético , Ritmo Circadiano , Teste de Esforço , Feminino , Frequência Cardíaca , Humanos , Hidrocortisona/sangue , Masculino , Pessoa de Meia-Idade , Testosterona/sangue
4.
Nat Commun ; 6: 6983, 2015 Apr 29.
Artigo em Inglês | MEDLINE | ID: mdl-25923318

RESUMO

Quantum data are susceptible to decoherence induced by the environment and to errors in the hardware processing it. A future fault-tolerant quantum computer will use quantum error correction to actively protect against both. In the smallest error correction codes, the information in one logical qubit is encoded in a two-dimensional subspace of a larger Hilbert space of multiple physical qubits. For each code, a set of non-demolition multi-qubit measurements, termed stabilizers, can discretize and signal physical qubit errors without collapsing the encoded information. Here using a five-qubit superconducting processor, we realize the two parity measurements comprising the stabilizers of the three-qubit repetition code protecting one logical qubit from physical bit-flip errors. While increased physical qubit coherence times and shorter quantum error correction blocks are required to actively safeguard the quantum information, this demonstration is a critical step towards larger codes based on multiple parity measurements.

5.
Eur J Appl Physiol ; 113(2): 325-35, 2013 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-22711181

RESUMO

This study compared the effects of mixed maximal strength and explosive strength training with maximal strength training and explosive strength training combined with endurance training over an 8-week training intervention. Male subjects (age 21-45 years) were divided into three strength training groups, maximal (MAX, n = 11), explosive (EXP, 10) and mixed maximal and explosive (MIX, 9), and a circuit training control group, (CON, 7). Strength training one to two times a week was performed concurrently with endurance training three to four times a week. Significant increases in maximal dynamic strength (1RM), countermovement jump (CMJ), maximal muscle activation during 1RM in MAX and during CMJ in EXP, peak running speed (S (peak)) and running speed at respiratory compensation threshold (RCT(speed)) were observed in MAX, EXP and MIX. Maximal isometric strength and muscle activation, rate of force development (RFD), maximal oxygen uptake [Formula: see text] and running economy (RE) at 10 and 12 km hr(-1) did not change significantly. No significant changes were observed in CON in maximal isometric strength, RFD, CMJ or muscle activation, and a significant decrease in 1RM was observed in the final 4 weeks of training. RE in CON did not change significantly, but significant increases were observed in S (peak), RCT(speed) and [Formula: see text] Low volume MAX, EXP and MIX strength training combined with higher volume endurance training over an 8-week intervention produced significant gains in strength, power and endurance performance measures of S (peak) and RCT(speed), but no significant changes were observed between groups.


Assuntos
Contração Muscular/fisiologia , Força Muscular/fisiologia , Condução Nervosa/fisiologia , Junção Neuromuscular/fisiologia , Resistência Física/fisiologia , Treinamento Resistido/métodos , Corrida/fisiologia , Adaptação Fisiológica/fisiologia , Adulto , Humanos , Masculino , Pessoa de Meia-Idade , Esforço Físico/fisiologia , Adulto Jovem
6.
Scand J Med Sci Sports ; 23(2): 171-80, 2013 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-21812828

RESUMO

The aim of this study was to investigate whether nocturnal heart rate variability (HRV) can be used to predict changes in endurance performance during 28 weeks of endurance training. The training was divided into 14 weeks of basic training (BTP) and 14 weeks of intensive training periods (ITP). Endurance performance characteristics, nocturnal HRV, and serum hormone concentrations were measured before and after both training periods in 28 recreational endurance runners. During the study peak treadmill running speed (Vpeak ) improved by 7.5 ± 4.5%. No changes were observed in HRV indices after BTP, but after ITP, these indices increased significantly (HFP: 1.9%, P=0.026; TP: 1.7%, P=0.007). Significant correlations were observed between the change of Vpeak and HRV indices (TP: r=0.75, P<0.001; HFP: r=0.71, P<0.001; LFP: r=0.69, P=0.01) at baseline during ITP. In order to lead to significant changes in HRV among recreational endurance runners, it seems that moderate- and high-intensity training are needed. This study showed that recreational endurance runners with a high HRV at baseline improved their endurance running performance after ITP more than runners with low baseline HRV.


Assuntos
Adaptação Fisiológica , Frequência Cardíaca/fisiologia , Educação Física e Treinamento/métodos , Resistência Física/fisiologia , Corrida/fisiologia , Adulto , Distribuição da Gordura Corporal , Índice de Massa Corporal , Teste de Esforço , Humanos , Hidrocortisona/sangue , Masculino , Consumo de Oxigênio/fisiologia , Esforço Físico/fisiologia , Testosterona/sangue
7.
Nano Lett ; 10(12): 5020-4, 2010 Dec 08.
Artigo em Inglês | MEDLINE | ID: mdl-21038919

RESUMO

Scaling down the dimensions of thermoacoustic sound sources (thermophones) improves efficiency by means of reducing speaker heat capacity. Recent experiments with nanoscale thermophones have revealed properties which are not fully understood theoretically. We develop a Green's function formalism which quantitatively explains some observed discrepancies, e.g., the effect of a heat-absorbing substrate in the proximity of the sound source. We also find a generic ultimate limit for thermophone efficiency. We verify the theory with experiments and finite difference method simulations which deal with thermoacoustically operated suspended arrays of nanowires. The efficiency of our devices is measured to be 1 order of magnitude below the ultimate bound. At low frequencies this mainly results from the presence of a substrate. At high frequencies, on the other hand, the efficiency is limited by the heat capacity of the nanowires. Measured sound pressure level and efficiency are in good agreement with simulations. We discuss the feasibility of reaching the ultimate limit in practice.

8.
Int J Sports Med ; 31(7): 468-76, 2010 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-20432192

RESUMO

This study examined effects of periodized maximal versus explosive strength training and reduced strength training, combined with endurance training, on neuromuscular and endurance performance in recreational endurance runners. Subjects first completed 6 weeks of preparatory strength training. Then, groups of maximal strength (MAX, n=11), explosive strength (EXP, n=10) and circuit training (C, n=7) completed an 8-week strength training intervention, followed by 14 weeks of reduced strength training. Maximal strength (1RM) and muscle activation (EMG) of leg extensors, countermovement jump (CMJ), maximal oxygen uptake (VO(2MAX)), velocity at VO(2MAX) (vVO(2MAX)) running economy (RE) and basal serum hormones were measured. 1RM and CMJ improved (p<0.05) in all groups accompanied by increased EMG in MAX and EXP (p<0.05) during strength training. Minor changes occurred in VO(2MAX), but vVO(2MAX) improved in all groups (p<0.05) and RE in EXP (p<0.05). During reduced strength training 1RM and EMG decreased in MAX (p<0.05) while vVO(2MAX) in MAX and EXP (p<0.05) and RE in MAX (p<0.01) improved. Serum testosterone and cortisol remained unaltered. Maximal or explosive strength training performed concurrently with endurance training was more effective in improving strength and neuromuscular performance and in enhancing vVO (2MAX) and RE in recreational endurance runners than concurrent circuit and endurance training.


Assuntos
Desempenho Atlético/fisiologia , Resistência Física/fisiologia , Treinamento Resistido , Adulto , Humanos , Hidrocortisona/sangue , Masculino , Pessoa de Meia-Idade , Força Muscular , Consumo de Oxigênio , Corrida/fisiologia , Testosterona/sangue , Adulto Jovem
9.
Int J Sports Med ; 31(6): 428-32, 2010 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-20419617

RESUMO

This study examined the effects of endurance exercise on nocturnal autonomic modulation. Nocturnal R-R intervals were collected after a rest day, after a moderate endurance exercise and after a marathon run in ten healthy, physically active men. Heart rate variability (HRV) was analyzed as a continuous four-hour period starting 30 min after going to bed for sleep. In relation to average nocturnal heart rate after rest day, increases to 109+/-6% and 130+/-11% of baseline were found after moderate endurance exercise and marathon, respectively. Standard deviation of R-R intervals decreased to 90+/-9% and 64+/-10%, root-mean-square of differences between adjacent R-R intervals to 87+/-10% and 55+/-16%, and high frequency power to 77+/-19% and 34+/-19% of baseline after moderate endurance exercise and marathon, respectively. Also nocturnal low frequency power decreased to 56+/-26% of baseline after the marathon. Changes in nocturnal heart rate and HRV suggest prolonged dose-response effects on autonomic modulation after exercises, which may give useful information on the extent of exercise-induced nocturnal autonomic modulation and disturbance to the homeostasis.


Assuntos
Exercício Físico/fisiologia , Frequência Cardíaca/fisiologia , Resistência Física/fisiologia , Adulto , Análise de Variância , Homeostase/fisiologia , Humanos , Masculino , Corrida/fisiologia
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