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Arch Soc Esp Oftalmol (Engl Ed) ; 99(6): 248-251, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38309660

RESUMO

Intrastromal antibiotic injections are a type of treatment that can be very useful in bacterial keratitis refractory to topical antibiotics. We present the case of a 44-year-old woman with an infiltrate in a laser in situ keratomiuleusis (LASIK) flap and growth of Achromobacter xylosoxidans, who was treated with topical ceftazidime for 1 month. However, after discontinuation of the antibiotic, there was a worsening with growth of the same germ. Topical treatment was reintroduced and, due to suspicion of germ reservoir, it was decided to give three cycles of intrastromal ceftazidime injections, the last one also with moxifloxacin, with good results. After 4 months asymptomatic and without treatment at the moment, no signs of recurrence have been observed. This case supports the usefulness of intraestromal injections in refractory cases to the topical medication.


Assuntos
Achromobacter denitrificans , Antibacterianos , Ceftazidima , Infecções por Bactérias Gram-Negativas , Ceratomileuse Assistida por Excimer Laser In Situ , Retalhos Cirúrgicos , Humanos , Feminino , Adulto , Achromobacter denitrificans/isolamento & purificação , Infecções por Bactérias Gram-Negativas/tratamento farmacológico , Antibacterianos/uso terapêutico , Antibacterianos/administração & dosagem , Ceratomileuse Assistida por Excimer Laser In Situ/efeitos adversos , Ceftazidima/uso terapêutico , Ceftazidima/administração & dosagem , Moxifloxacina/uso terapêutico , Moxifloxacina/administração & dosagem , Infecções Oculares Bacterianas/tratamento farmacológico , Ceratite/tratamento farmacológico , Ceratite/microbiologia , Substância Própria , Complicações Pós-Operatórias/tratamento farmacológico , Fluoroquinolonas/uso terapêutico , Fluoroquinolonas/administração & dosagem
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