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Mater Sci Eng C Mater Biol Appl ; 57: 288-93, 2015 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-26354266

RESUMO

This paper addresses the mechanical characterization of polycaprolactone (PCL)-bioglass (FastOs®BG) composites and scaffolds intended for use in tissue engineering. Tissue engineering scaffolds support the self-healing mechanism of the human body and promote the regrowth of damaged tissue. These implants can dissolve after successful tissue regeneration minimising the immune reaction and the need for revision surgery. However, their mechanical properties should match surrounding tissue in order to avoid strain concentration and possible separation at the interface. Therefore, an extensive experimental testing programme of this advanced material using uni-axial compressive testing was conducted. Tests were performed at low strain rates corresponding to quasi-static loading conditions. The initial elastic gradient, plateau stress and densification strain were obtained. Tested specimens varied according to their average density and material composition. In total, four groups of solid and robocast porous PCL samples containing 0, 20, 30, and 35% bioglass, respectively were tested. The addition of bioglass was found to slightly decrease the initial elastic gradient and the plateau stress of the biomaterial scaffolds.


Assuntos
Substitutos Ósseos/síntese química , Cerâmica/química , Poliésteres/química , Engenharia Tecidual/instrumentação , Alicerces Teciduais , Força Compressiva , Módulo de Elasticidade , Desenho de Equipamento , Análise de Falha de Equipamento , Dureza , Teste de Materiais , Estresse Mecânico , Resistência à Tração
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