1.
Chem Commun (Camb)
; 49(34): 3561-3, 2013 May 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23525259
RESUMO
Up to six differently substituted highly challenging angularly-oxygenated tricyclic core models of natural angucyclinones were stereoselectively synthesized from a common p-quinol intermediate obtained from Oxone-mediated oxidative dearomatization of the corresponding tricyclic phenol.
Assuntos
Antraquinonas/química , Fenóis/química , Ácidos Sulfúricos/química , Hidroquinonas/química , Oxirredução
2.
Org Biomol Chem
; 9(3): 758-64, 2011 Feb 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21082125
RESUMO
The synthesis of the C15-C26 fragment of (-)-dictyostatin is reported in 10 steps and 28% overall yield. The key steps are the two stereoselective sulfoxide-directed processes: a Reformatsky-type reaction and a ß-keto sulfoxide reduction.